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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22677 | Cobimetinib racemate | Cobimetinib (racemate) | MEK |
Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated protein kinase, is a key component of the RAS/RAF/MEK/ERK pathwa... | |||
T10856 | Cobimetinib (R-enantiomer) | XL-518 R-enantiomer,Cobimetinib R-enantiomer,GDC-0973 R-enantiomer | Others |
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor. | |||
T5054 | GSK963 | GSK963 (Racemate) | RIP kinase |
GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM). | |||
T13450L | GNE-140 racemate | GNE-140 (racemate) | Others |
GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. | |||
T11178L | ELN318463 racemate | ELN318463 (racemate),ELN 318463 racemate | Gamma-secretase |
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor. | |||
T16440 | Ibrutinib Racemate | PCI-32765 (Racemate) | Others |
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib. | |||
T13814 | Pemafibrate (racemate) | K13675 (racemate) | Others |
Pemafibrate racemate is the racemate of pemafibrate | |||
T12866 | SCH 42495 racemate | SCH 42495 (racemate) | Others |
SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral inhibitor of metalloendopeptidase (NEP), with antihypertensive effect. | |||
T13313 | Seviteronel racemate | VT-464 (racemate) | Others |
Seviteronel racemate is the racemate form of Seviteronel and is a potent inhibitor of CYP17 lyase. | |||
T64175 | Cobimetinib hemifumarate | ||
Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1. | |||
T10591 | BPO-27 racemate | BPO-27 (racemate) | CFTR , Autophagy |
BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM. | |||
T3623 | Cobimetinib | RG7420,XL518,GDC-0973 | Apoptosis , MEK |
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e... |