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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12352 | Oxidopamine hydrochloride | 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist. | |||
T12352L | Oxidopamine hydrobromide | 6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist. | |||
TN1644 | Flavanomarein | Others | |
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea... | |||
T27012 | Chrysotoxine | Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-,4-[2-(3,4-Dimethoxyphenyl)ethyl]-2,6-dimethoxyphenol | NF-κB |
Chrysotoxine (Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-) inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection. | |||
T5S2357 | Acetylcorynoline | (+)-Corynoline Acetate,O-Acetylcorynoline | Antifungal |
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3... | |||
T3803 | Specnuezhenide | Nuzhenide,Nuezhenide | Others , NF-κB , Wnt/beta-catenin |
Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t... | |||
T40951 | ABT-107 | ||
ABT-107, a selective α7 neuronal nicotinic receptor agonist, demonstrates neuroprotective effects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions. | |||
T28793 | SKF-80723 HBr | SKF80723 Hydrobromide,SKF 80723 HBr,SKF-80723 Hydrobromide,SKF 80723 Hydrobromide | |
SKF-80723 HBr is a D1 receptor agonist. SKF-80723 HBr strongly potentiated the contralateral circling induced by quinpirole in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle. | |||
T27959 | LY503430 | LY-503430,LY 503430 | |
LY503430 is a AMPA receptor potentiator with oral activity. LY503430 has both nootropic and neuroprotective effects, reducing brain damage caused by 6-hydroxydopamine or MPTP. | |||
T33858 | PACA | N-Propargyl Caffeamide | |
PACA, (N-propargyl Caffeamide)enhances NGF-induced neurite growth and reduces 6-hydroxydopamine neurotoxicity in neuron cultures. Parkinson's disease (PD) is associated with insufficient production of nerve growth factor... | |||
T82058 | Inubritannolide A | ||
Inubritannolide A exhibits moderate to robust neuroprotective effects across various neuronal cell types against inducers such as H2O2, 6-hydroxydopamine (6-OHDA), and lipopolysaccharide (LPS). | |||
TN1653 | Fustin | ERK , Beta Amyloid , AChR | |
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death. | |||
T20396 | Levadopa Related Compound A | 6-Hydroxydopa, L-,L-Hydroxydopa | |
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent... |