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SKF-80723 HBr

Catalog No. T28793   CAS 71636-62-9
Synonyms: SKF80723 Hydrobromide, SKF 80723 HBr, SKF-80723 Hydrobromide, SKF 80723 Hydrobromide

SKF-80723 HBr is a D1 receptor agonist. SKF-80723 HBr strongly potentiated the contralateral circling induced by quinpirole in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle.

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SKF-80723 HBr Chemical Structure
SKF-80723 HBr, CAS 71636-62-9
Pack Size Availability Price/USD Quantity
25 mg 6-8 weeks $ 1,520.00
50 mg 6-8 weeks $ 1,980.00
100 mg 6-8 weeks $ 2,500.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description SKF-80723 HBr is a D1 receptor agonist. SKF-80723 HBr strongly potentiated the contralateral circling induced by quinpirole in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle.
Synonyms SKF80723 Hydrobromide, SKF 80723 HBr, SKF-80723 Hydrobromide, SKF 80723 Hydrobromide
Molecular Weight 334.21
Formula C16H16BrNO2
CAS No. 71636-62-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Gnanalingham KK, Hunter AJ, Jenner P, Marsden CD. The differential behavioural effects of benzazepine D1 dopamine agonists with varying efficacies, co-administered with quinpirole in primate and rodent models of Parkinson's disease. Psychopharmacology (Berl). 1995 Feb;117(3):287-97. PubMed PMID: 7770604. 2. Starr MS, Starr BS. Seizure promotion by D1 agonists does not correlate with other dopaminergic properties. J Neural Transm Park Dis Dement Sect. 1993;6(1):27-34. PubMed PMID: 8105796. 3. Gnanalingham KK, Hunter AJ, Jenner P, Marsden CD. Stimulation of adenylate cyclase activity by benzazepine D-1 dopamine agonists with varying efficacies in the 6-hydroxydopamine lesioned rat--relationship to circling behaviour. Biochem Pharmacol. 1995 May 11;49(9):1185-93. PubMed PMID: 7763300. 4. Alam AM, Starr MS. D1 agonists suppress zero Mg(2+)-induced epileptiform activity in the rat cingulate cortex slice. Neuroreport. 1993 Oct 25;5(1):78-80. PubMed PMID: 7506591.

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Keywords

SKF-80723 HBr 71636-62-9 SKF80723 HBr SKF80723 Hydrobromide SKF 80723 HBr SKF-80723 Hydrobromide SKF 80723 Hydrobromide inhibitor inhibit

 

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