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Search Results for " 5-ht2c "

20

Compounds

Cat No. Product Name Synonyms Targets
T22514 4F 4PP oxalate 5-HT Receptor
4F 4PP oxalate is a 5-HT2A antagonist.
T8357 SB-200646 5-HT Receptor
SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor
T39161 Ro60-0175 Ro60-0175 5-HT Receptor
Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B recept...
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T1445 Agomelatine Thymanax,S-20098,Valdoxan Melatonin Receptor , 5-HT Receptor
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
T6241 Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T79802 5-HT2C agonist-3 5-HT Receptor
5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced hyperactivity [1].
T79806 5-HT2A&5-HT2C agonist-1 5-HT Receptor
5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM. It is applicable in the study of various central nervous system disor...
T79803 5-HT2C agonist-3 free base 5-HT Receptor
5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-induced hyperactivity [1].
T68565 ANN33840
ANN33840 is a novel selective 5-HT2C agonist with >300-fold functional selectivity over 5-HT2B and >70-fold functional selectivity over 5-HT2A, reducing food intake in an acute rat feeding model.
T10871 CP-809101 hydrochloride 5-HT Receptor
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
T13332 (Rac)-WAY-161503 5-HT Receptor
(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.
T16856 SB228357 5-HT Receptor
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
T13275 Vabicaserin hydrochloride SCA 136 5-HT Receptor
Vabicaserin hydrochloride (SCA 136) is a selective agonist of 5-hydroxytryptamine 2C (5-HT2C) receptor (EC50: 8 nM).
T5158 N-Desmethylclozapine Desmethylclozapine,Normethylclozapine,Norclozapine Virus Protease , Dopamine Receptor , 5-HT Receptor , Opioid Receptor , AChR , Drug Metabolite
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors.
T22947 LY266097 hydrochloride LY 266097 hydrochloride 5-HT Receptor
LY266097 hydrochloride (LY 266097 hydrochloride) is an antagonist of 5-HT2 with pKis of 7.7, 9.8, and 7.6 for human 5-HT2A, 5-HT2B, and 5-HT2C and can be used in studies about depression.
T7350 Nelotanserin APD125 5-HT Receptor
Nelotanserin (APD125) is a potent 5-HT2A inverse agonist(IC50 : 1.7 nM), a moderately potent 5-HT2C partial inverse agonist t(IC50 :79 nM )and a weak 5-HT2B inverse agonistt(IC50 : 791 nM).
T16401 Org-12962 5-HT Receptor
Org-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A and 5-HT2B receptor...
T12489L Pimethixene maleate Pimetixene maleate Dopamine Receptor , 5-HT Receptor , AChR , Histamine Receptor
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as we...
T23168 PNU 22394 hydrochloride 5-HT Receptor
PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist

Compounds

4F 4PP oxalate
T22514
Synonym:
Target: 5-HT Receptor
SB-200646
T8357
Synonym:
Target: 5-HT Receptor
Ro60-0175
T39161
Synonym: Ro60-0175
Target: 5-HT Receptor
Quetiapine
T0162
Synonym: ICI204636,Quetiapin
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
Agomelatine
T1445
Synonym: Thymanax,S-20098,Valdoxan
Target: Melatonin Receptor, 5-HT Receptor
Quetiapine hemifumarate
T6241
Synonym: Quetiapine Fumarate,ICI-204636
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
5-HT2C agonist-3
T79802
Synonym:
Target: 5-HT Receptor
5-HT2A&5-HT2C agonist-1
T79806
Synonym:
Target: 5-HT Receptor
5-HT2C agonist-3 free base
T79803
Synonym:
Target: 5-HT Receptor
ANN33840
T68565
Synonym:
Target:
CP-809101 hydrochloride
T10871
Synonym:
Target: 5-HT Receptor
(Rac)-WAY-161503
T13332
Synonym:
Target: 5-HT Receptor
SB228357
T16856
Synonym:
Target: 5-HT Receptor
Vabicaserin hydrochloride
T13275
Synonym: SCA 136
Target: 5-HT Receptor
N-Desmethylclozapine
T5158
Synonym: Desmethylclozapine,Normethylclozapine,Norclozapine
Target: Virus Protease, Dopamine Receptor, 5-HT Receptor, Opioid Receptor, AChR, Drug Metabolite
LY266097 hydrochloride
T22947
Synonym: LY 266097 hydrochloride
Target: 5-HT Receptor
Nelotanserin
T7350
Synonym: APD125
Target: 5-HT Receptor
Org-12962
T16401
Synonym:
Target: 5-HT Receptor
Pimethixene maleate
T12489L
Synonym: Pimetixene maleate
Target: Dopamine Receptor, 5-HT Receptor, AChR, Histamine Receptor
PNU 22394 hydrochloride
T23168
Synonym:
Target: 5-HT Receptor
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TargetMol