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SB228357

SB228357
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Purity:99.31%
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SB228357

Catalog No. T16856Cas No. 181629-93-6
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
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Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$178In Stock
10 mg$297In Stock
25 mg$491In Stock
50 mg$654In Stock
100 mg$894In Stock
1 mL x 10 mM (in DMSO)$169In Stock
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Product Introduction

Bioactivity
Description
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
In vivo
In male Sprague Dawley rats, oral administration of SB228357 (0-10 mg/kg) reverses Haloperidol-induced catalepsy obviously[2].
Chemical Properties
Molecular Weight431.38
FormulaC22H17F4N3O2
Cas No.181629-93-6
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 38.9 mg/mL (90.1 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3181 mL11.5907 mL23.1814 mL115.9071 mL
5 mM0.4636 mL2.3181 mL4.6363 mL23.1814 mL
10 mM0.2318 mL1.1591 mL2.3181 mL11.5907 mL
20 mM0.1159 mL0.5795 mL1.1591 mL5.7954 mL
50 mM0.0464 mL0.2318 mL0.4636 mL2.3181 mL

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