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Search Results for " 5-ht2a "

20

Compounds

Cat No. Product Name Synonyms Targets
T10498 5-HT2A antagonist 1 5-HT Receptor
5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.
T0280 Spiperone Spiroperidol,Spiropitan Dopamine Receptor
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
T11217 Eplivanserin SR-46349 5-HT Receptor
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
TQ0084 Lumateperone Tosylate ITI-007 Dopamine Receptor , 5-HT Receptor
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM).
T6241 Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T79155 5-HT2A receptor agonist-3 5-HT Receptor
5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM. It also demonstrates a remarkable 124-fold selectivity over its structurally an...
T79806 5-HT2A&5-HT2C agonist-1 5-HT Receptor
5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM. It is applicable in the study of various central nervous system disor...
T61220 5-HT6/5-HT2A receptor ligand-2
Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properti...
T8136 Perospirone hydrochloride Perospirone HCl,SM-9018 hydrochloride Dopamine Receptor , 5-HT Receptor
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
T61507 5-HT2A receptor agonist-2
5-HT2A receptor agonist-2 is a potent compound that acts as an agonist on the serotonin 5-HT2 receptor. It specifically stimulates the 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors, with EC 50 values of 1.7 nM, 0.58 nM, and 0....
T61207 5-HT6/5-HT2A receptor ligand-1
5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual antagonist for the 5-HT6 and 5-HT2A receptors. It exhibits a K i value of 2 nM and 11 nM for the respective receptors. This compound holds promise for research in ne...
T21069 Lumateperone ITI 722,ITI722,ITI-007,ITI007 5-HT Receptor
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).
T14083 Abaperidone Dopamine Receptor , 5-HT Receptor
Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th...
T10871 CP-809101 hydrochloride 5-HT Receptor
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
T15034 Roluperidone CYR-101,MIN-101,MT-210 Sigma receptor , 5-HT Receptor
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and σ2).
T22514 4F 4PP oxalate 5-HT Receptor
4F 4PP oxalate is a 5-HT2A antagonist.
T17033 Temanogrel APD791 5-HT Receptor
Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).
T16856 SB228357 5-HT Receptor
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
T6946 Pimavanserin tartrate ACP-103,ACP-103 tartrate,Nuplazid,Pimavanserin 5-HT Receptor
Pimavanserin tartrate (Nuplazid) is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease.

Compounds

5-HT2A antagonist 1
T10498
Synonym:
Target: 5-HT Receptor
Spiperone
T0280
Synonym: Spiroperidol,Spiropitan
Target: Dopamine Receptor
Eplivanserin
T11217
Synonym: SR-46349
Target: 5-HT Receptor
Quetiapine
T0162
Synonym: ICI204636,Quetiapin
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
lumateperone Tosylate
TQ0084
Synonym: ITI-007
Target: Dopamine Receptor, 5-HT Receptor
Quetiapine hemifumarate
T6241
Synonym: Quetiapine Fumarate,ICI-204636
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
5-HT2A receptor agonist-3
T79155
Synonym:
Target: 5-HT Receptor
5-HT2A&5-HT2C agonist-1
T79806
Synonym:
Target: 5-HT Receptor
5-HT6/5-HT2A receptor ligand-2
T61220
Synonym:
Target:
Perospirone hydrochloride
T8136
Synonym: Perospirone HCl,SM-9018 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor
5-HT2A receptor agonist-2
T61507
Synonym:
Target:
5-HT6/5-HT2A receptor ligand-1
T61207
Synonym:
Target:
Lumateperone
T21069
Synonym: ITI 722,ITI722,ITI-007,ITI007
Target: 5-HT Receptor
Abaperidone
T14083
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
CP-809101 hydrochloride
T10871
Synonym:
Target: 5-HT Receptor
Roluperidone
T15034
Synonym: CYR-101,MIN-101,MT-210
Target: Sigma receptor, 5-HT Receptor
4F 4PP oxalate
T22514
Synonym:
Target: 5-HT Receptor
Temanogrel
T17033
Synonym: APD791
Target: 5-HT Receptor
SB228357
T16856
Synonym:
Target: 5-HT Receptor
Pimavanserin tartrate
T6946
Synonym: ACP-103,ACP-103 tartrate,Nuplazid,Pimavanserin
Target: 5-HT Receptor
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TargetMol