Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins. TGFB proteins are produced by all white blood cell lineages. Activated TGF-β complexes with other factors to form a serine/threonine kinase complex that binds to TGF-β receptors. TGF-β receptors are composed of both type 1 and type 2 receptor subunits. After the binding of TGF-β, the type 2 receptor kinase phosphorylates and activates the type 1 receptor kinase that activates a signaling cascade. This leads to the activation of different downstream substrates and regulatory proteins. TGF-β also plays a crucial role in stem cell differentiation as well as T-cell regulation and differentiation. Because of its role in immune and stem cell regulation and differentiation, it is a highly researched cytokine in the fields of cancer, auto-immune diseases, and infectious disease.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPY-03945 | Latent TGF beta 1 Protein, Rat, Recombinant (His)
Latent TGF beta 1 Protein, Rat, Recombinant (His)
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Rat | HEK293 Cells |
Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accessi... | |||
TMPY-00608 | TGF beta 1 Protein, Rat/Mouse, Recombinant
TGF beta 1 Protein, Rat/Mouse, Recombinant
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Mouse,Rat | HEK293 Cells |
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa. | |||
TMPY-04211 | Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa. | |||
TMPY-02638 | TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
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Human,Rhesus,Cynomolgus,Canine | CHO Cells |
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession... | |||
TMPY-00500 | Latent TGF beta 1 Protein, Mouse, Recombinant (His)
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 Cells |
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the acces... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His)
GDF-15 Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
GDF-15 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q99988. | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc)
GDF-15 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
GDF-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number... | |||
TMPY-06247 | TGF beta 3 Protein, Human, Recombinant (hFc)
TGF beta 3 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession nu... | |||
TMPJ-00249 | TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
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Human | HEK293 Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and ... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
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Human,Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted a... | |||
TMPJ-00258 | TGF beta 2 Protein, Human, Recombinant
TGF beta 2 Protein, Human, Recombinant
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Human | HEK293 Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular fun... | |||
TMPJ-00261 | TGF beta 2 Protein, Mouse/Rat, Recombinant
TGF beta 2 Protein, Mouse/Rat, Recombinant
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Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deleti... | |||
TMPJ-01471 | Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
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Human/Mouse/Rat | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfami... | |||
TMPY-01133 | Latent TGF beta 1 Protein, Human, Recombinant (His)
Latent TGF beta 1 Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the acces... | |||
TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293)
GDNF Protein, Human, Recombinant (HEK293)
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Human | HEK293 Cells |
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2... |