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Interleukins, ILs

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (22)
Feline (2)
Human (137)
Marmoset (3)
Mouse (67)
Rabbit (5)
Rat (17)
Rhesus (8)
Sus scrofa (Pig) (3)
Expression System
Baculovirus Insect Cells (18)
CHO Cells (3)
E. coli (105)
HEK293 Cells (142)
P. pastoris (Yeast) (4)
Tag
Avi (1)
C-6xHis (17)
C-6xHis-Avi (3)
C-Avi (1)
C-Avi-6xHis (1)
C-C-His (1)
C-His (40)
C-His-Avi (15)
C-hFc (21)
C-hIgG2 hFc (1)
C-hIgG4 hFc (1)
C-mFc (5)
Fc-Flag (1)
Fc-His (1)
Flag (1)
GST (1)
His (27)
N-6xHis (3)
N-His (18)
N-His-Avi (13)
N-hFc (3)
Tag Free (92)
hFc (10)
Cat No. product name / Synonyms Species Expression System
TMPJ-00020 IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5...
TMPJ-00030 IL-1F10 Protein, Human, Recombinant
IL-1F10 Protein, Human, Recombinant
Human E. coli
Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate imm...
TMPJ-00034 IL-4 Protein, Human, Recombinant (hFc)
IL-4 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number...
TMPJ-00036 IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 16-18 K...
TMPJ-00046 IL-17F Protein, Human, Recombinant
IL-17F Protein, Human, Recombinant
Human E. coli
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mi...
TMPJ-00047 IL-31 Protein, Human, Recombinant
IL-31 Protein, Human, Recombinant
Human E. coli
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncos...
TMPJ-00060 IL-25/IL17E Protein, Human, Recombinant (His)
IL-25/IL17E Protein, Human, Recombinant (His)
Human HEK293 Cells
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins...
TMPJ-00061 IL-22 Protein, Human, Recombinant (hIgG2 hFc)
IL-22 Protein, Human, Recombinant (hIgG2 hFc)
Human HEK293 Cells
IL-22 Protein, Human, Recombinant (hIgG2 hFc) is expressed in HEK293 mammalian cells with C-hIgG2 Fc tag. The predicted molecular weight is 50-62 KDa and the acc...
TMPJ-00062 IL-22 Protein, Human, Recombinant (hIgG4 hFc)
IL-22 Protein, Human, Recombinant (hIgG4 hFc)
Human HEK293 Cells
IL-22 Protein, Human, Recombinant (hIgG4 hFc) is expressed in HEK293 mammalian cells with C-hIgG4 Fc tag. The predicted molecular weight is 50-75 KDa and the acc...
TMPJ-00070 IL-18 Protein, Human, Recombinant (His)
IL-18 Protein, Human, Recombinant (His)
Human HEK293 Cells
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cyt...
TMPJ-00072 IL-18BPd Protein, Mouse, Recombinant (hFc)
IL-18BPd Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, wh...
TMPJ-00074 IL-18BP Protein, Human, Recombinant (hFc)
IL-18BP Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mo...
TMPJ-00077 IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 24-2...
TMPJ-00078 IL-17C Protein, Human, Recombinant (His)
IL-17C Protein, Human, Recombinant (His)
Human HEK293 Cells
IL-17C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession numb...
TMPJ-00079 IL-11 Protein, Mouse, Recombinant (hFc)
IL-11 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-indu...
TMPJ-00080 IL-11 Protein, Human, Recombinant (P. pastoris)
IL-11 Protein, Human, Recombinant (P. pastoris)
Human P. pastoris (Yeast)
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growt...
TMPJ-00161 IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated
Human E. coli
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 K...
TMPJ-00216 IL-12B Protein, Human, Recombinant
IL-12B Protein, Human, Recombinant
Human HEK293 Cells
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-1...
TMPJ-00451 IL-16 Protein, Human, Recombinant
IL-16 Protein, Human, Recombinant
Human E. coli
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration s...
TMPJ-00573 IL-17F Protein, Human, Recombinant (His)
IL-17F Protein, Human, Recombinant (His)
Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession numb...
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00020
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5...
IL-1F10 Protein, Human, Recombinant
TMPJ-00030
Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate imm...
IL-4 Protein, Human, Recombinant (hFc)
TMPJ-00034
IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number...
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00036
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 16-18 K...
IL-17F Protein, Human, Recombinant
TMPJ-00046
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mi...
IL-31 Protein, Human, Recombinant
TMPJ-00047
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncos...
IL-25/IL17E Protein, Human, Recombinant (His)
TMPJ-00060
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins...
IL-22 Protein, Human, Recombinant (hIgG2 hFc)
TMPJ-00061
IL-22 Protein, Human, Recombinant (hIgG2 hFc) is expressed in HEK293 mammalian cells with C-hIgG2 Fc tag. The predicted molecular weight is 50-62 KDa and the acc...
IL-22 Protein, Human, Recombinant (hIgG4 hFc)
TMPJ-00062
IL-22 Protein, Human, Recombinant (hIgG4 hFc) is expressed in HEK293 mammalian cells with C-hIgG4 Fc tag. The predicted molecular weight is 50-75 KDa and the acc...
IL-18 Protein, Human, Recombinant (His)
TMPJ-00070
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cyt...
IL-18BPd Protein, Mouse, Recombinant (hFc)
TMPJ-00072
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, wh...
IL-18BP Protein, Human, Recombinant (hFc)
TMPJ-00074
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mo...
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00077
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 24-2...
IL-17C Protein, Human, Recombinant (His)
TMPJ-00078
IL-17C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession numb...
IL-11 Protein, Mouse, Recombinant (hFc)
TMPJ-00079
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-indu...
IL-11 Protein, Human, Recombinant (P. pastoris)
TMPJ-00080
Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growt...
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00161
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 K...
IL-12B Protein, Human, Recombinant
TMPJ-00216
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-1...
IL-16 Protein, Human, Recombinant
TMPJ-00451
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration s...
IL-17F Protein, Human, Recombinant (His)
TMPJ-00573
IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession numb...
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TargetMol