Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00035 | IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st... | |||
TMPK-00041 | IL-17F Protein, Mouse, Recombinant (His & Avi)
IL-17F Protein, Mouse, Recombinant (His & Avi)
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Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the acce... | |||
TMPK-00042 | IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kD... | |||
TMPK-00043 | IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | E. coli |
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto... | |||
TMPK-00046 | IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /1... | |||
TMPK-00049 | IL-3 Protein, Mouse, Recombinant (hFc)
IL-3 Protein, Mouse, Recombinant (hFc)
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Mouse | HEK293 Cells |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet... | |||
TMPK-00051 | IL-20 Protein, Human, Recombinant (hFc)
IL-20 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent... | |||
TMPK-00052 | IL-20 Protein, Human, Recombinant (His)
IL-20 Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent... | |||
TMPK-00055 | IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/I... | |||
TMPK-00056 | IL-10 Protein, Human, Recombinant (His & Avi)
IL-10 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 Cells |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet... | |||
TMPK-00057 | IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet... | |||
TMPK-00060 | IL-17B Protein, Mouse, Recombinant (His)
IL-17B Protein, Mouse, Recombinant (His)
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Mouse | E. coli |
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tu... | |||
TMPK-00076 | IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
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Human | E. coli |
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12.... | |||
TMPK-00082 | IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar... | |||
TMPK-00084 | IL-17C Protein, Human, Recombinant (His & Avi)
IL-17C Protein, Human, Recombinant (His & Avi)
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Human | HEK293 Cells |
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines ... | |||
TMPK-00088 | IL-11 Protein, Human, Recombinant (His)
IL-11 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can... | |||
TMPK-00089 | IL-11 Protein, Cynomolgus, Recombinant (His)
IL-11 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can... | |||
TMPK-00101 | IL-6 Protein, Cynomolgus, Recombinant (His)
IL-6 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interl... | |||
TMPK-00161 | IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
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Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe... | |||
TMPK-00162 | IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe... |