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Interleukins, ILs

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (22)
Feline (2)
Human (137)
Marmoset (3)
Mouse (67)
Rabbit (5)
Rat (17)
Rhesus (8)
Sus scrofa (Pig) (3)
Expression System
Baculovirus Insect Cells (18)
CHO Cells (3)
E. coli (105)
HEK293 Cells (142)
P. pastoris (Yeast) (4)
Tag
Avi (1)
C-6xHis (17)
C-6xHis-Avi (3)
C-Avi (1)
C-Avi-6xHis (1)
C-Flag (1)
C-His (59)
C-His-Avi (15)
C-hFc (27)
C-hFc-Flag (1)
C-hFc-His (1)
C-hIgG2 hFc (1)
C-hIgG4 hFc (1)
C-mFc (5)
His (2)
N-6xHis (3)
N-GST (1)
N-His (25)
N-His-Avi (13)
N-hFc (6)
Tag Free (92)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPK-00035 IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
TMPK-00041 IL-17F Protein, Mouse, Recombinant (His & Avi)
IL-17F Protein, Mouse, Recombinant (His & Avi)
Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the acce...
TMPK-00042 IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kD...
TMPK-00043 IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
Human E. coli
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto...
TMPK-00046 IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /1...
TMPK-00049 IL-3 Protein, Mouse, Recombinant (hFc)
IL-3 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00051 IL-20 Protein, Human, Recombinant (hFc)
IL-20 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent...
TMPK-00052 IL-20 Protein, Human, Recombinant (His)
IL-20 Protein, Human, Recombinant (His)
Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent...
TMPK-00055 IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/I...
TMPK-00056 IL-10 Protein, Human, Recombinant (His & Avi)
IL-10 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet...
TMPK-00057 IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet...
TMPK-00060 IL-17B Protein, Mouse, Recombinant (His)
IL-17B Protein, Mouse, Recombinant (His)
Mouse E. coli
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tu...
TMPK-00076 IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
Human E. coli
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12....
TMPK-00082 IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
TMPK-00084 IL-17C Protein, Human, Recombinant (His & Avi)
IL-17C Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines ...
TMPK-00088 IL-11 Protein, Human, Recombinant (His)
IL-11 Protein, Human, Recombinant (His)
Human HEK293 Cells
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can...
TMPK-00089 IL-11 Protein, Cynomolgus, Recombinant (His)
IL-11 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can...
TMPK-00101 IL-6 Protein, Cynomolgus, Recombinant (His)
IL-6 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interl...
TMPK-00161 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
TMPK-00162 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00035
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
IL-17F Protein, Mouse, Recombinant (His & Avi)
TMPK-00041
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the acce...
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00042
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kD...
IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00043
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto...
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00046
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /1...
IL-3 Protein, Mouse, Recombinant (hFc)
TMPK-00049
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-20 Protein, Human, Recombinant (hFc)
TMPK-00051
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent...
IL-20 Protein, Human, Recombinant (His)
TMPK-00052
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potent...
IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00055
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/I...
IL-10 Protein, Human, Recombinant (His & Avi)
TMPK-00056
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet...
IL-10 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00057
Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association bet...
IL-17B Protein, Mouse, Recombinant (His)
TMPK-00060
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tu...
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
TMPK-00076
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12....
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00082
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
IL-17C Protein, Human, Recombinant (His & Avi)
TMPK-00084
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines ...
IL-11 Protein, Human, Recombinant (His)
TMPK-00088
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can...
IL-11 Protein, Cynomolgus, Recombinant (His)
TMPK-00089
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human can...
IL-6 Protein, Cynomolgus, Recombinant (His)
TMPK-00101
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interl...
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
TMPK-00161
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00162
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
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TargetMol