Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00163 | IL-33 Protein, Cynomolgus, Recombinant (His)
IL-33 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellul... | |||
TMPK-00491 | IL-18BP Protein, Cynomolgus, Recombinant (His)
IL-18BP Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar... | |||
TMPK-00492 | IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
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Cynomolgus | HEK293 Cells |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar... | |||
TMPK-00515 | IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe... | |||
TMPK-00568 | IL-9 Protein, Cynomolgus, Recombinant (His)
IL-9 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce... | |||
TMPK-00590 | IL-3 Protein, Human, Recombinant (E. coli)
IL-3 Protein, Human, Recombinant (E. coli)
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Human | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet... | |||
TMPK-00617 | IL-13 Protein, Human, Recombinant (His & Avi)
IL-13 Protein, Human, Recombinant (His & Avi)
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Human | HEK293 Cells |
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is s... | |||
TMPK-00655 | IL-3 Protein, Cynomolgus, Recombinant (His)
IL-3 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet... | |||
TMPK-00661 | IL-22 Protein, Cynomolgus, Recombinant (His)
IL-22 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function,... | |||
TMPK-00769 | IL-2 Protein, Mouse, Recombinant (His & Avi)
IL-2 Protein, Mouse, Recombinant (His & Avi)
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Mouse | HEK293 Cells |
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o... | |||
TMPK-00770 | IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o... | |||
TMPK-00771 | IL-5 Protein, Mouse, Recombinant (His & Avi)
IL-5 Protein, Mouse, Recombinant (His & Avi)
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Mouse | HEK293 Cells |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b... | |||
TMPK-00772 | IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b... | |||
TMPK-00919 | IL-4 Protein, Cynomolgus, Recombinant (His)
IL-4 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st... | |||
TMPK-00920 | IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 Cells |
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were ... | |||
TMPK-00975 | IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kD... | |||
TMPK-01036 | IL-17A Protein, Mouse, Recombinant (His & Avi)
IL-17A Protein, Mouse, Recombinant (His & Avi)
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Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the access... | |||
TMPK-01037 | IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa ... | |||
TMPK-01169 | IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | HEK293 Cells |
The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative... | |||
TMPK-01172 | IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
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Mouse | E. coli |
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto... |