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Interleukins, ILs

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (22)
Feline (2)
Human (137)
Marmoset (3)
Mouse (67)
Rabbit (5)
Rat (17)
Rhesus (8)
Sus scrofa (Pig) (3)
Expression System
Baculovirus Insect Cells (18)
CHO Cells (3)
E. coli (105)
HEK293 Cells (142)
P. pastoris (Yeast) (4)
Tag
Avi (1)
C-6xHis (17)
C-6xHis-Avi (3)
C-Avi (1)
C-Avi-6xHis (1)
C-Flag (1)
C-His (59)
C-His-Avi (15)
C-hFc (27)
C-hFc-Flag (1)
C-hFc-His (1)
C-hIgG2 hFc (1)
C-hIgG4 hFc (1)
C-mFc (5)
His (2)
N-6xHis (3)
N-GST (1)
N-His (25)
N-His-Avi (13)
N-hFc (6)
Tag Free (92)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPK-00163 IL-33 Protein, Cynomolgus, Recombinant (His)
IL-33 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellul...
TMPK-00491 IL-18BP Protein, Cynomolgus, Recombinant (His)
IL-18BP Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
TMPK-00492 IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Cynomolgus HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
TMPK-00515 IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
TMPK-00568 IL-9 Protein, Cynomolgus, Recombinant (His)
IL-9 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
TMPK-00590 IL-3 Protein, Human, Recombinant (E. coli)
IL-3 Protein, Human, Recombinant (E. coli)
Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00617 IL-13 Protein, Human, Recombinant (His & Avi)
IL-13 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is s...
TMPK-00655 IL-3 Protein, Cynomolgus, Recombinant (His)
IL-3 Protein, Cynomolgus, Recombinant (His)
Cynomolgus E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00661 IL-22 Protein, Cynomolgus, Recombinant (His)
IL-22 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function,...
TMPK-00769 IL-2 Protein, Mouse, Recombinant (His & Avi)
IL-2 Protein, Mouse, Recombinant (His & Avi)
Mouse HEK293 Cells
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o...
TMPK-00770 IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o...
TMPK-00771 IL-5 Protein, Mouse, Recombinant (His & Avi)
IL-5 Protein, Mouse, Recombinant (His & Avi)
Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
TMPK-00772 IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
TMPK-00919 IL-4 Protein, Cynomolgus, Recombinant (His)
IL-4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
TMPK-00920 IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were ...
TMPK-00975 IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kD...
TMPK-01036 IL-17A Protein, Mouse, Recombinant (His & Avi)
IL-17A Protein, Mouse, Recombinant (His & Avi)
Mouse HEK293 Cells
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the access...
TMPK-01037 IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa ...
TMPK-01169 IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative...
TMPK-01172 IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse E. coli
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto...
IL-33 Protein, Cynomolgus, Recombinant (His)
TMPK-00163
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellul...
IL-18BP Protein, Cynomolgus, Recombinant (His)
TMPK-00491
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00492
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway ar...
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
TMPK-00515
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processe...
IL-9 Protein, Cynomolgus, Recombinant (His)
TMPK-00568
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
IL-3 Protein, Human, Recombinant (E. coli)
TMPK-00590
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-13 Protein, Human, Recombinant (His & Avi)
TMPK-00617
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is s...
IL-3 Protein, Cynomolgus, Recombinant (His)
TMPK-00655
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-22 Protein, Cynomolgus, Recombinant (His)
TMPK-00661
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function,...
IL-2 Protein, Mouse, Recombinant (His & Avi)
TMPK-00769
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o...
IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00770
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities o...
IL-5 Protein, Mouse, Recombinant (His & Avi)
TMPK-00771
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00772
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
IL-4 Protein, Cynomolgus, Recombinant (His)
TMPK-00919
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
TMPK-00920
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were ...
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00975
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kD...
IL-17A Protein, Mouse, Recombinant (His & Avi)
TMPK-01036
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the access...
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01037
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa ...
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01169
The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative...
IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01172
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cyto...
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TargetMol