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Interleukins, ILs

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (22)
Feline (2)
Human (137)
Marmoset (3)
Mouse (67)
Rabbit (5)
Rat (17)
Rhesus (8)
Sus scrofa (Pig) (3)
Expression System
Baculovirus Insect Cells (18)
CHO Cells (3)
E. coli (105)
HEK293 Cells (142)
P. pastoris (Yeast) (4)
Tag
Avi (1)
C-6xHis (17)
C-6xHis-Avi (3)
C-Avi (1)
C-Avi-6xHis (1)
C-Flag (1)
C-His (59)
C-His-Avi (15)
C-hFc (27)
C-hFc-Flag (1)
C-hFc-His (1)
C-hIgG2 hFc (1)
C-hIgG4 hFc (1)
C-mFc (5)
His (2)
N-6xHis (3)
N-GST (1)
N-His (25)
N-His-Avi (13)
N-hFc (6)
Tag Free (92)
hFc (1)
Cat No. product name / Synonyms Species Expression System
TMPJ-00594 IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
Human HEK293 Cells
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 ...
TMPJ-00596 IL-13 Protein, Human, Recombinant (mFc)
IL-13 Protein, Human, Recombinant (mFc)
Human HEK293 Cells
IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession numb...
TMPJ-00617 IL-33 Protein, Rhesus macaque, Recombinant (His)
IL-33 Protein, Rhesus macaque, Recombinant (His)
Rhesus E. coli
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph node...
TMPJ-00633 IL-17F Protein, Cynomolgus, Recombinant (His)
IL-17F Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
IL-17F Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19-22 KDa and the access...
TMPJ-00877 IL-2 Protein, Rat, Recombinant (His)
IL-2 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ an...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His)
IL-18 Protein, Mouse, Recombinant (His)
Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, ga...
TMPJ-01234 IL-36 gamma Protein, Mouse, Recombinant
IL-36 gamma Protein, Mouse, Recombinant
Mouse E. coli
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-...
TMPJ-01237 IL-17D Protein, Human, Recombinant
IL-17D Protein, Human, Recombinant
Human E. coli
The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cyst...
TMPJ-01316 IL-21 Protein, Mouse, Recombinant (His)
IL-21 Protein, Mouse, Recombinant (His)
Mouse E. coli
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence id...
TMPJ-01339 IL-22 Protein, Mouse, Recombinant (E. coli)
IL-22 Protein, Mouse, Recombinant (E. coli)
Mouse E. coli
IL-22 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is Q9JJY...
TMPJ-01340 IL-22 Protein, Mouse, Recombinant (mFc)
IL-22 Protein, Mouse, Recombinant (mFc)
Mouse HEK293 Cells
IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession numb...
TMPJ-01392 IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)
IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)
Cavia porcellus E. coli
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) a...
TMPJ-01444 IL-17A Protein, Cynomolgus, Recombinant (His)
IL-17A Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mi...
TMPK-00021 IL-5 Protein, Human, Recombinant (His & Avi)
IL-5 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
TMPK-00025 IL-9 Protein, Human, Recombinant (hFc)
IL-9 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
TMPK-00026 IL-9 Protein, Mouse, Recombinant (hFc)
IL-9 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
TMPK-00031 IL-3 Protein, Human, Recombinant (His & Avi)
IL-3 Protein, Human, Recombinant (His & Avi)
Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00032 IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00033 IL-3 Protein, Human, Recombinant (hFc)
IL-3 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
TMPK-00034 IL-4 Protein, Human, Recombinant (His & Avi)
IL-4 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00594
IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 ...
IL-13 Protein, Human, Recombinant (mFc)
TMPJ-00596
IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession numb...
IL-33 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00617
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph node...
IL-17F Protein, Cynomolgus, Recombinant (His)
TMPJ-00633
IL-17F Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19-22 KDa and the access...
IL-2 Protein, Rat, Recombinant (His)
TMPJ-00877
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ an...
IL-18 Protein, Mouse, Recombinant (His)
TMPJ-01056
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, ga...
IL-36 gamma Protein, Mouse, Recombinant
TMPJ-01234
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-...
IL-17D Protein, Human, Recombinant
TMPJ-01237
The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cyst...
IL-21 Protein, Mouse, Recombinant (His)
TMPJ-01316
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence id...
IL-22 Protein, Mouse, Recombinant (E. coli)
TMPJ-01339
IL-22 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is Q9JJY...
IL-22 Protein, Mouse, Recombinant (mFc)
TMPJ-01340
IL-22 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession numb...
IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)
TMPJ-01392
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) a...
IL-17A Protein, Cynomolgus, Recombinant (His)
TMPJ-01444
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mi...
IL-5 Protein, Human, Recombinant (His & Avi)
TMPK-00021
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will b...
IL-9 Protein, Human, Recombinant (hFc)
TMPK-00025
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
IL-9 Protein, Mouse, Recombinant (hFc)
TMPK-00026
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial ce...
IL-3 Protein, Human, Recombinant (His & Avi)
TMPK-00031
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00032
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-3 Protein, Human, Recombinant (hFc)
TMPK-00033
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoiet...
IL-4 Protein, Human, Recombinant (His & Avi)
TMPK-00034
Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the st...
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TargetMol