Powder: -20°C for 3 years | In solvent: -80°C for 1 year
YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
2 mg | In stock | $ 137.00 | |
5 mg | In stock | $ 198.00 | |
10 mg | In stock | $ 359.00 | |
25 mg | In stock | $ 577.00 | |
50 mg | In stock | $ 823.00 | |
100 mg | In stock | $ 1,090.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 237.00 |
Description | YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13. |
Targets&IC50 | CDK7-CyclinH-MAT1:9.7 nM |
Molecular Weight | 515.61 |
Formula | C28H33N7O3 |
CAS No. | 1957203-01-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 220 mg/mL (426.68 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
YKL-5-124 1957203-01-8 Cell Cycle/Checkpoint CDK T-loop phosphorylation inhibit arrest CDK7 Inhibitor YKL5124 YKL 5 124 CDK7/Mat1/CycH Cyclin dependent kinase cell-cycle transcription Pol-II irreversible covalent inhibitor