cdk7 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40264	CDK7-IN-7	CDK7-IN-7
	CDK7-IN-7, a highly potent and selective inhibitor of CDK7 kinase, exhibits remarkable activity with an IC50 of less than 50 nM.
T39943	CDK7-IN-6	CDK7-IN-6
	CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. Thi...
T39372	CDK7-IN-1	CDK7-IN-1
	CDK7-IN-1 is an analog derived from YKL-5-124 and functions as an inhibitor of cyclin-dependent kinase 7 (cdk7). It exhibits strong inhibitory activity, with an IC50 value of less than 100 nM (WO 2016105528 A2, Compound ...
T39247	CDK7-IN-5	CDK7-IN-5
	CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).
T40353	CDK7/9-IN-1	CDK7/9-IN-1
	CDK7/9-IN-1 is a specific inhibitor of cyclin-dependent kinases 7/9 (CDK7/9). It specifically targets CDK7, while also displaying inhibitory activity against CDK9. CDK7/9-IN-1 demonstrates excellent inhibitory potency ag...
T36038	SY-5609	CDK7-IN-3	CDK
	SY-5609 is a selective and noncovalent inhibitor of CDK7(KD = 0.065 nM) with antitumor activity and inhibits apoptosis.		CDK
T7296	THZ2	CDK7-IN-1	CDK
	THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).		CDK
T39864	CDK7-IN-2 hydrochloride hydrate	CDK7-IN-2 hydrochloride hydrate
	CDK7-IN-2 hydrochloride hydrate (Example 6) is a highly effective and specific inhibitor of the CDK7 enzyme. This compound exhibits significant anti-cancer properties.
T3664	THZ1	CDK7 inhibitor,THZ1 2HCl	CDK
	THZ1 (CDK7 inhibitor) is a novel selective and potent covalent CDK7 inhibitor.		CDK
T36743	CDK7/9 tide
	CDK7/9 tide is peptide substrate for CDK7 or CDK9[1]. [1]. Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27; 8:1...
T63301	CDK7-IN-18
	CDK7-IN-18 is a pyrimidine-derived compound that is a potent inhibitor of CDK7. CDK7-IN-18 exhibits potential for research in a variety of cancers, particularly those with dysregulated transcription.
T79881	CDK7-IN-25		CDK
	CDK7-IN-25 (CY-16-1) is a potent CDK7 inhibitor with an IC50 value of less than 1nM, utilized in cancer research [1].		CDK
T62791	CDK7-IN-16
	CDK7-IN-16 (Compound 9) is a potent inhibitor of CDK 7 (IC50: 1-10 nM). CDK7-IN-16 can be used in research against cancer, particularly cancers with transcriptional abnormalities.
T79169	CDK7-IN-22		CDK
	CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].		CDK
T75121	CDK7-IN-21
	CDK7-IN-21 (compound A22) is a potent CDK7 inhibitor [1] .
T63410	CDK7-IN-17
	CDK7-IN-17 is a pyrimidine-derived compound and a potent inhibitor of CDK7. CDK7-IN-17 has shown research potential for a variety of cancers, particularly those with dysregulated transcription.
T63108	CDK7-IN-14
	CDK7-IN-14 is a pyrimidine-derived compound that is a potent inhibitor of CDK7. CDK7-IN-14 has the potential to be investigated in a variety of cancers, particularly those with transcriptional dysregulation.
T63381	CDK7-IN-8
	CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.
T63724	CDK7-IN-10
	CDK7-IN-10 is a CDK7 inhibitor (IC50<100 nM). CDK7-IN-10 inhibits kinase activity and has the potential to inhibit cell growth and induce apoptosis.
T61922	CDK7-IN-12
	CDK7-IN-12 is an effective CDK7 inhibitor and plays a key role in regulating transcription and cell cycle. CDK7-IN-12 can effectively inhibit the proliferation of malignant tumors in vitro and in vivo. CDK7-IN-12 has res...