Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 347.00 | |
25 mg | In stock | $ 589.00 | |
50 mg | In stock | $ 842.00 | |
100 mg | In stock | $ 1,160.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents. |
Targets&IC50 | mGluR3:392 nM |
Molecular Weight | 387.8 |
Formula | C18H15ClFN5O2 |
CAS No. | 1809085-30-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: insoluble
DMSO: 240 mg/mL (618.88 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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VU0650786 1809085-30-0 Neuroscience GluR inhibit VU 0650786 anxiolytic activity antidepressant Inhibitor mGlu3 NAM VU-0650786 mGluR Metabotropic glutamate receptors inhibitor