Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 54.00 | |
5 mg | In stock | $ 117.00 | |
10 mg | In stock | $ 177.00 | |
25 mg | In stock | $ 363.00 | |
50 mg | In stock | $ 562.00 | |
100 mg | In stock | $ 790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 169.00 |
Description | Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells. |
In vitro | Solamargine concentration-dependently reduced HepG2 cell viability. Solamargine (7.5 μM) reduced cell viability by less than 20% in HepG2 cells. Solamargine (highest dose) decreased cell invasion and migration by more than 72% and 70% in HepG2 cells, respectively. Solamargine reduced function and expression of MMP-2/9 proteins. Solamargine time-dependently increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) in a fashion. |
Source |
Synonyms | Solamargin, δ-Solanigrine |
Molecular Weight | 868.06 |
Formula | C45H73NO15 |
CAS No. | 20311-51-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 91 mg/mL(104.8 mM)
You can also refer to dose conversion for different animals. More
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Solamargine 20311-51-7 Apoptosis JAK/STAT signaling MAPK Membrane transporter/Ion channel Neuroscience Stem Cells p38 MAPK P-gp STAT Inhibitor cytotoxicity cells Cluster of differentiation 243 MDR1 Pgp Solamargin P-glycoprotein ABCB1 inhibit cancer gastric delta-Solanigrine δ-Solanigrine Multidrug resistance protein 1 CD243 HepG2 inhibitor