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Sanggenon C

Catalog No. T4S1615 CAS 80651-76-9

Synonyms: Sanggenone C

1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.

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Sanggenon C, CAS 80651-76-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 97.00
5 mg	In stock	$ 247.00
10 mg	In stock	$ 368.00
25 mg	In stock	$ 593.00
50 mg	In stock	$ 848.00
100 mg	In stock	$ 1,160.00
1 mL * 10 mM (in DMSO)	In stock	$ 349.00

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Purity: 98.49%

Purity: 98.35%

Purity: 97.76%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Moraceae > Morus

Synonyms	Sanggenone C
Molecular Weight	708.71
Formula	C40H36O12
CAS No.	80651-76-9

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 7.09 mg/mL (10 mM), Sonication is recommended.

References and Literature

1. Huang H , Liu N , Zhao K , et al. Sanggenon C decreases tumor cell viability associated with proteasome inhibition[J]. Front Biosci, 2011, 3(4):1315-1325.

Citations

1. Liu X, Zhu Y, Wang D, et al.The natural compound Sanggenon C inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway.Veterinary Research.2023, 54(1): 1-16. 2. Liu X, Meng Y, He J, et al.Natural compound Sanggenon C inhibits porcine reproductive and respiratory syndrome virus replication in piglets.Veterinary Microbiology.2024, 290: 109991.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Inhibitor Library Anti-Cancer Compound Library Antioxidant Compound Library Bioactive Compound Library Flavonoid Natural Product Library Natural Product Library for HTS Anti-Aging Compound Library Natural Product Library Polyphenolic Natural Product Library

Related Products

Related compounds with same targets

NF-κB-IN-8 Glabrol 6,4'-Dihydroxy-7-methoxyflavanone Suberosin MyD88-IN-1 Veraguensin Rocaglamide CTP-NBD

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sanggenon C 80651-76-9 NF-Κb NF-κB Inhibitor Nuclear factor-kappaB Sanggenone C Nuclear factor-κB inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.