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ER alpha Protein, Human, Recombinant (His)
(Synonyms: Nuclear Receptor Subfamily 3 Group A Member 1, NR3A1, estrogen receptor α, estrogen receptor alpha, Estrogen Receptor, Estradiol Receptor, ESR1, ESR, ER-α, ER-Alpha, ER α, ER alpha, ER) Copy Product InfoSynonyms: Nuclear Receptor Subfamily 3 Group A Member 1, NR3A1, estrogen receptor α, estrogen receptor alpha, Estrogen Receptor, Estradiol Receptor, ESR1, ESR, ER-α, ER-Alpha, ER α, ER alpha, ER
Catalog No. TMPJ-00762 Copy Product Info
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 7-10 days | 7-10 days | |
| 10 μg | $183 | 7-10 days | 7-10 days | |
| 20 μg | $292 | 7-10 days | 7-10 days | |
| 50 μg | $545 | 7-10 days | 7-10 days | |
| 100 μg | $792 | 7-10 days | 7-10 days | |
| 200 μg | $1,150 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | P03372 |
| Amino Acid | Met1-Gln116 |
| Construction | Met1-Gln116 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Glycine-HCl, 8% Sucrose, 0.05% Tween 80, pH 3.5. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Nuclear Receptor Subfamily 3 Group A Member 1, NR3A1, estrogen receptor α, estrogen receptor alpha, Estrogen Receptor, Estradiol Receptor, ESR1, ESR, ER-α, ER-Alpha, ER α, ER alpha, ER |
| Research Background |
| Molecular Weight | 14 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: ER alpha Protein, Human, Recombinant (His) chemical structure | ER alpha Protein, Human, Recombinant (His) molecular weight
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