store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
2 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 449.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,880.00 |
Description | Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects. |
In vitro | In follicle-enclosed Xenopus oocytes, Dimethindene (5-500 μM) decreases Cromakalim cromakalim-induced K+ currents (IC50 = 29.5 μM)[1]. |
In vivo | In C57BL/6 mice with skin wound healing, Dimethindene (0.25 mg; i.p.) impairs cutaneous wound healing and delays skin wound closure[2]. |
Synonyms | Dimetindeno, Z 2001, Dimetindene, Z-2001, Z2001 |
Molecular Weight | 292.42 |
Formula | C20H24N2 |
CAS No. | 5636-83-9 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dimethindene 5636-83-9 GPCR/G Protein Immunology/Inflammation Membrane transporter/Ion channel Metabolism Neuroscience Potassium Channel Histamine Receptor AChR Endogenous Metabolite Dimetindeno Z 2001 Dimetindene Z-2001 Z2001 inhibitor inhibit