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Cholic acid sodium

Catalog No. T4537   CAS 361-09-1
Synonyms: SodiumCholate

Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.

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Cholic acid sodium Chemical Structure
Cholic acid sodium, CAS 361-09-1
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Purity: 99.95%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
In vivo Cholic acid (sodium cholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.?The same effects are observed for F-5 Gel, the active mixture of a new contraceptive sponge (Protectaid), which contains sodium cholate in association with low concentrations (0.5%) of nonoxynol-9 and benzalkonium chloride.?Both cholic acid and the F-5 Gel exert a dose-dependent, in-vitro inhibitory effect (i) on the activity of HIV-1 associated reverse transcriptase in an acellular system and (ii) on the potential of HIV-1 efficiently to infect human lymphocytes.
Synonyms SodiumCholate
Molecular Weight 430.55
Formula C24H39NaO5
CAS No. 361-09-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 86 mg/mL (199.74 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Psychoyos A , Creatsas G , Hassan E , et al. Spermicidal and antiviral properties of cholic acid: contraceptive efficacy of a new vaginal sponge (ProtectaidR) containing sodium cholate[J]. Human Reproduction(6):6.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Viral Compound Library Bioactive Compound Library FDA-Approved & Pharmacopeia Drug Library Clinical Compound Library Natural Product Library for HTS Human Metabolite Library RO5 Drug-like Natural Product Library Bioactive Compounds Library Max Approved Drug Library Anti-Infection Compound Library

Related Products

Related compounds with same targets
Adenosine 5'-diphosphate sodium salt Spaglumic acid acetate Uridine triphosphate Ecdysone 7α,25-Dihydroxycholesterol Triiodothyronine Sulfate Acetoacetic acid lithium salt S-Adenosyl-L-methionine

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Keywords

Cholic acid sodium 361-09-1 Metabolism Microbiology/Virology Proteases/Proteasome Endogenous Metabolite HIV Protease glycine HepG2 cholesterol excretion inhibit Cholic acid Inhibitor SodiumCholate taurine inhibitor

 

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