Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 41.00 | |
10 mg | In stock | $ 57.00 | |
25 mg | In stock | $ 124.00 | |
50 mg | In stock | $ 197.00 | |
100 mg | In stock | $ 316.00 | |
200 mg | In stock | $ 476.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively) |
Targets&IC50 | Kainate:1.5 μM, AMPA:0.3 μM |
In vitro | In rat hippocampal slices bathed in Mg2+-free medium 10 microM CNQX reversibly blocks responses to alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), quisqualate and kainate but not NMDA. The synaptic response evoked by low frequency stimulation of Schaffer collateral-commissural fibres in 1 mM Mg2+-containing medium is completely blocked by this concentration of CNQX. In contrast the synaptic response evoked in Mg2+-free medium is not fully blocked by CNQX[1]. |
Synonyms | FG9065 |
Molecular Weight | 232.15 |
Formula | C9H4N4O4 |
CAS No. | 115066-14-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (129.23 mM)
You can also refer to dose conversion for different animals. More
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CNQX 115066-14-3 Membrane transporter/Ion channel Neuroscience GluR iGluR fear-potentiated startle AMPA FG 9065 FG9065 non-NMDA kainate inhibit Inhibitor FG-9065 Ionotropic glutamate receptors inhibitor