Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Berberine sulfate (Berberal) is a quaternary ammonium salt of the benzylisoquinoline alkaloid proto-berberines, which can be used in the study of type 2 diabetes mellitus, abdominal obesity and metabolism-related fatty liver disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 39.00 | |
50 mg | In stock | $ 51.00 | |
100 mg | In stock | $ 68.00 | |
500 mg | In stock | $ 165.00 |
Description | Berberine sulfate (Berberal) is a quaternary ammonium salt of the benzylisoquinoline alkaloid proto-berberines, which can be used in the study of type 2 diabetes mellitus, abdominal obesity and metabolism-related fatty liver disease. |
In vitro |
Berberine sulfate (1.25-160 μM; 72 h) has a potential inhibitory effect on the proliferation of four colorectal cancer cell lines, LoVo, HCT116, SW480, and HT-29.[5] Berberine suLfate (1.25-160 μM; 24-72 h) induces time- and dose-dependent inhibition of LoVo cell growth.[5] LoVo cells were exposed to Berberine sulfate (10 -80 μM) for 24 hours. Cell cycle analysis of LoVo cells treated with 40 μM berberine by flow cytometry showed an accumulation of cells in the G2/M phase.[5] Berberine sulfate (10 -80 μM) inhibits the expression of cyclin B1, cdc2, and cdc25c proteins after 24 hours, especially at the dose of 80.0 μM.[5] |
In vivo | Berberine sulfate (10, 30, or 50 mg/kg/day; gastrointestinal gavage; 10 consecutive days) inhibits the growth of human colorectal adenocarcinoma in vivo. Berberine (30 and 50 mg/kg/d; gastrointestinal gavage) inhibited the growth of human colorectal adenocarcinoma xenografts in nude mice by 33.1% and 45.3%, respectively.[5] |
Synonyms | AI3-61947, Berberin sulfate, Berberine sulphate, Berberal |
Molecular Weight | 768.78 |
Formula | C40H36N2O12S |
CAS No. | 316-41-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 7.69 mg/mL (10 mM), Sonication is recommended.
H2O: 38.46 mg/mL (50.03 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Berberine sulfate 316-41-6 AI3-61947 Berberin sulfate Berberine Sulfate Berberin Sulfate Berberine sulphate Berberal inhibitor inhibit