tyrosinase — TargetMol Chemicals

Cat No.	Product Name	Targets
T73598	Tyrosinase
	Tyrosinase (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin and is encoded by TYR gene. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes [1] .
T78554	Tyrosinase-IN-12	Tyrosinase
	Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25 µM. Tyrosinase-IN-12 has significant antioxidant and free r...	Tyrosinase
T67939	Tyrosinase-IN-16
	Tyrosinase-IN-16 inhibited tyrosinase.
T60278	Tyrosinase-IN-2	Tyrosinase
	Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase, a copper-containing metalloenzyme pivotal for the catalytic step that limits the rate in melanin biosynthesis and enzymatic browning processes. This comp...	Tyrosinase
TP1623	[Asp371]-Tyrosinase (369-377), human
	Tyrosinase (369-377,YMDGTMSQV) is derived from the membrane protein tyrosinase by posttranslational conversion of the sequence YMNGTMSQV. Presentation of YMDGTMSQV in cells expressing full-length tyrosinase is TAP-(trans...
T39311	Tyrosinase-related Protein 2 (TRP-2) (181-188)
	Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from the tyrosinase-related protein 2 (TRP-2), specifically corresponding to residues 180-188. It is the primary epitope within TRP-2 that is recognized...
T60484	Tyrosinase-IN-4
	Tyrosinase-IN-4 (compound 34) is a potent tyrosinase inhibitor. As a promising target, tyrosinase inhibitors can be used as skin-whitening agents and food preservatives. Tyrosinase-IN-4 has the potential in the fields of...
T80910	Tyrosinase-IN-15	Tyrosinase
	Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].	Tyrosinase
T61460	Tyrosinase-IN-3
	Tyrosinase-IN-3 (compound 54) is a powerful tyrosinase inhibitor, an enzyme involved in the key catalytic step of melanin biosynthesis and enzymatic browning. As a copper-containing metalloenzyme, tyrosinase plays a cruc...
T72786	Tyrosinase-IN-7
	Tyrosinase-IN-7, a potent inhibitor of tyrosinase, exhibits an IC50 value of 1.57 µM and demonstrates inhibition of cell growth with minimal cytotoxicity.
T72787	Tyrosinase-IN-8
	Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity while effectively inhibiting cell growth.
T60449	Tyrosinase-IN-1
	Tyrosinase-IN-1 (compound 90) is a potent tyrosinase inhibitor. As a promising target, tyrosinase inhibitors can be used as skin-whitening agents and food preservatives, thus having broad potential in the fields of food,...
T61817	Tyrosinase-IN-6
	Tyrosinase-IN-6 (Compound 4B) demonstrated the highest efficacy as a tyrosinase inhibitor (ic50 = 3.80 μM), in addition to exhibiting favorable antioxidant activity.
T72703	Tyrosinase-IN-11
	Tyrosinase-IN-11, a potent inhibitor of tyrosinase, exhibits IC50 values of 50 nM and 64 nM for L-tyrosinase and L-dopa (L-dopa), respectively. It demonstrates significant antioxidant activity coupled with low cytotoxici...
T80909	Tyrosinase-IN-19	Tyrosinase
	Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals and demonstrates dose-dependent suppression of tyrosinase expression...	Tyrosinase
T61425	Tyrosinase-IN-5
	Tyrosinase-IN-5 (compound 16c) is a highly effective inhibitor of tyrosinase, exhibiting an IC50 value of 0.02 μM. This compound efficiently suppresses melanogenesis while posing minimal toxicity to cells [1].
T72720	Tyrosinase-IN-10
	Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme's activity in lysates derived from human melanoma cells.
T79406	Tyrosinase-IN-14	Tyrosinase
	Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity, and possesses anti-browning properties that effectively pr...	Tyrosinase
T79401	Tyrosinase-IN-13	Tyrosinase
	Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM and 36.3 μM respectively. This compound demonstrates cytotoxici...	Tyrosinase
T80911	Tyrosinase (192-200), human mouse
	Tyrosinase (192-200), a human mouse nonapeptide, is recognizable by cytolytic T cells (CTL) on the HLA-B44 molecule and is utilized in the research of melanoma-associated cancers [1].