Traditional Chinese Medicine Monomer Library

Catalog No. L6810

Library Compound List Excel SDF

Traditional Chinese medicine has been practiced for thousands of years to treat or prevent diseases. However, its physical foundation, mode of action, and prescription compatibility of TCM pharmacodynamic action were not determined in complete detail, and the complexity of formulae greatly limited the research of effective constituents related with the clinical efficacy of TCM. The therapeutic efficacy of TCMs is mainly based on the combined action of a mixture of active phytochemical constituents. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, Artemisinin, the active ingredient extracted from a Chinese herb Artemisia annua L, is the most effective antimalarial drug. Ginsenosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine. Therefore, it is a good and economical way with less risk to discover new chemical drugs based on active ingredients and leading compounds separating from Chinese herbal medicine. With the continuous development of the traditional Chinese medicine industry especially in separation methods and isolation techniques in recent years, it has been proved that traditional Chinese medicine (TCM) monomers, the active compounds of Chinese Herbal Medicines, have many medicinal properties and can effectively guide innovative drug discovery.

TCM can contribute to addressing a number of global health challenges of the 21st Century, in particular in the area of chronic, noncommunicable diseases and population aging.

TargetMol’s Traditional Chinese Medicine Monomer Library collects 2771 compounds that all come from about 800 Chinese Herbal Medicines, such as Panax natoginseng, Licorice, Angelica, Pericarpium Citri Reticulatae, Coptis chinensis, Panax ginseng, etc., containing chemical structures such as Flavonoids, Alkaloids, Terpenes, Glycosides, etc. TargetMol’s Traditional Chinese Medicine Monomer Library is a useful tool for new drug discovery and mechanism studies in anti-cancer, anti-inflammatory, anti-bacterial, apoptosis, autophagy, etc.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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Product Description

A unique collection of 2771 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism；
Sources from about 800 Chinese Herbal Medicines, such as Panax natoginseng, Licorice, Angelica, Pericarpium Citri Reticulatae, Coptis chinensis, Panax ginseng, etc.;
Diversified structures including Flavonoids, Alkaloids, Terpenes, Glycosides, etc.；
NMR and HPLC validated to ensure high purity and quality；
All compounds are in stock with fast shipping.

Library Customization

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Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Nature Communications. 2023, 14(1): 1020.. 2. Clinical and Translational Medicine. 2023, 13(8): e1359. 3. Acta Pharmacologica Sinica. 2022: 1-9.. 4. Cell Stem Cell. 2022 Apr 29(4) 545–558. 5. Science Bulletin. 2022. 6. Science Translational Medicine. 2022, 14(656): eabn3231. 7. Science Advances. 2023, 9(9): eade3760. 8. Nature. 2020, 582: 289-293. 9. Nature Biotechnology. 2021, 39(11): 1444-1452.

10. Nature Communications. 2022, 13(1): 1-15.. 11. Nature Communications. 2023, 14(1): 2756.. 12. Blood. 2021, 137(11): 1478-1490. 13. Nucleic Acids Research. 2021. 14. Nature Communications. 2023, 14(1): 7574. 15. Advanced Science. 2020, 7(16): 2000925. 16. Angewandte Chemie. 2021. 17. Acta Pharmaceutica Sinica B. 2022. 18. Protein & Cell. 2021, 12(11): 877-888. 19. Bone Research. 2023, 11(1): 54. 20. Pharmacology & Therapeutics. (2021): 107930. 21. Nature Communications. 2021, 12(1): 1-12. 22. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Endogenous Metabolite (468)

Apoptosis (326)

Antibacterial (212)

Autophagy (207)

NF-κB (164)

Antioxidant (104)

COX (95)

Antifungal (93)

Reactive Oxygen Species (85)

P450 (68)

Parasite (63)

TNF (59)

Influenza Virus (59)

AChR (49)

p38 MAPK (45)

AChE (44)

ERK (44)

Anti-infection (43)

HIV Protease (42)

IL Receptor (40)

Akt (40)

NO Synthase (39)

Antibiotic (39)

DNA/RNA Synthesis (37)

PPAR (36)

Calcium Channel (35)

Caspase (35)

GABA Receptor (35)

STAT (35)

AMPK (33)

Tyrosinase (32)

MMP (29)

PI3K (28)

5-HT Receptor (28)

JNK (28)

Virus Protease (28)

Ferroptosis (27)

ROS (26)

Nrf2 (26)

Lipoxygenase (25)

BCL (24)

Immunology/Inflammation related (23)

TRP/TRPV Channel (23)

Topoisomerase (23)

Mitophagy (22)

Estrogen Receptor/ERR (22)

Potassium Channel (22)

NOS (22)

PKC (21)

Estrogen/progestogen Receptor (20)

HSV (20)

Prostaglandin Receptor (20)

HBV (19)

PDE (19)

Antifection (19)

P-gp (19)

ATPase (19)

Beta Amyloid (18)

Dehydrogenase (18)

Glucosidase (17)

Adrenergic Receptor (17)

Antiviral (17)

Sodium Channel (16)

Microtubule Associated (16)

PARP (16)

Dopamine Receptor (15)

EGFR (15)

Wnt/beta-catenin (14)

Interleukin (14)

MAO (14)

HDAC (13)

JAK (13)

Phosphatase (12)

mTOR (12)

Reductase (11)

TLR (11)

Phospholipase (11)

HIF/HIF Prolyl-Hydroxylase (11)

TGF-beta/Smad (10)

Adenosine Receptor (10)

SARS-CoV (9)

Sirtuin (9)

HCV Protease (9)

Mitochondrial Metabolism (9)

RAAS (9)

MAPK (9)

MEK (8)

Androgen Receptor (8)

Nucleoside Antimetabolite/Analog (8)

Monoamine Oxidase (8)

Opioid Receptor (8)

CDK (8)

BACE (8)

Histamine Receptor (8)

Reverse Transcriptase (7)

IκB/IKK (7)

transporter (7)

Fatty Acid Synthase (7)

UGT (7)

VEGFR (7)

Cannabinoid Receptor (7)

HER (7)

HSP (7)

PKA (7)

p53 (6)

Platelet aggregation (6)

PAFR (6)

Chloride channel (6)

Indoleamine 2,3-Dioxygenase (IDO) (6)

Gamma-secretase (6)

LDL (6)

iGluR (6)

Drug Metabolite (6)

Carbonic Anhydrase (6)

MRP (6)

Beta-Secretase (5)

Epigenetic Reader Domain (5)

DNA (5)

Proteasome (5)

GPR (5)

Glucocorticoid Receptor (5)

HIF (5)

NMDAR (5)

GluR (4)

Amylase (4)

Free radical scavengers (4)

Xanthine Oxidase (4)

S6 Kinase (4)

cAMP (4)

IGF-1R (4)

HMG-CoA Reductase (4)

IAP (4)

Transferase (4)

CaMK (4)

NOD (4)

Aromatase (4)

cell cycle arrest (4)

Serine Protease (4)

PTEN (4)

Serotonin Transporter (4)

Syk (4)

GSK-3 (4)

Hedgehog/Smoothened (4)

FGFR (4)

PGE Synthase (4)

GST (3)

Telomerase (3)

Acyltransferase (3)

Proton pump (3)

Progesterone Receptor (3)

NADPH-oxidase (3)

DNA Alkylator/Crosslinker (3)

Ras (3)

NOD-like Receptor (NLR) (3)

FAK (3)

ROR (3)

CCR (3)

Aryl Hydrocarbon Receptor (3)

Histone Acetyltransferase (3)

PDGFR (3)

Tyrosine Kinases (3)

Trk receptor (3)

FAAH (3)

Lipid (3)

CXCR (3)

Integrin (3)

PAI-1 (2)

IRAK (2)

Imidazoline Receptor (2)

Aminopeptidase (2)

Retinoid Receptor (2)

ATM/ATR (2)

Thrombin (2)

RSV (2)

hCE (2)

Pyroptosis (2)

Casein Kinase (2)

Bombesin Receptor (2)

OAT (2)

c-Met/HGFR (2)

Adiponectin receptor (2)

NADPH (2)

RANKL/RANK (2)

Glucokinase (2)

Amino Acids and Derivatives (2)

Arginase (2)

Leukotriene Receptor (2)

Src (2)

Liver X Receptor (2)

Cysteine Protease (2)

Serine/threonin kinase (2)

Pim (2)

OCT (2)

Glutathione Peroxidase (2)

Lipase (2)

Bcr-Abl (2)

E1/E2/E3 Enzyme (2)

DPP-4 (2)

DHFR (2)

SGLT (2)

Monoamine Transporter (2)

Aurora Kinase (2)

Smo (2)

Norepinephrine (2)

CYP19A1 (1)

S1P Receptor (1)

P2Y Receptor (1)

LTR (1)

IFNAR (1)

aconitase (1)

RAR/RXR (1)

FLT (1)

DYRK (1)

Mdm2 (1)

DNA Methyltransferase (1)

Transaminase (1)

Adenylyl cyclase (1)

LPL Receptor (1)

Histone Methyltransferase (1)

PD-1/PD-L1 (1)

NPC1L1 (1)

stilbene oxidase (1)

CFTR (1)

TAM Receptor (1)

MyD88 (1)

AhR (1)

ROS Kinase (1)

Dynamin (1)

DNA-PK (1)

ATTECs (1)

Hydroxylase (1)

Histone Demethylase (1)

Raf (1)

ATP Citrate Lyase (1)

Thrombopoietin Receptor (1)

Epoxide Hydrolase (1)

PAD (1)

Stearoyl-CoA Desaturase (SCD) (1)

PAK (1)

advanced glycation end products (1)

CPT (1)

DNA gyrase (1)

P2X Receptor (1)

ALK (1)

Phosphorylase (1)

Glucagon Receptor (1)

Fas/FasL (1)

PERK (1)

MTH1 (1)

Prolyl Endopeptidase (PREP) (1)

IDO (1)

ribosome (1)

FXR (1)

CRISPR/Cas9 (1)

PDK (1)

Oxytocin Receptor (1)

CaSR (1)

Survivin (1)

ABC (1)

PLK (1)

Melatonin Receptor (1)

Factor Xa (1)

PKM (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty