Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 70.00 | |
25 mg | In stock | $ 114.00 | |
50 mg | In stock | $ 167.00 | |
100 mg | In stock | $ 248.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 58.00 |
Description | 5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi. |
In vitro | 5-Aminouridine inhibits the incorporation of carbamyl aspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma[1]. 5-Aminouridine must exhibit a low potential to be oxidized by Os(bpy)33+. The modified nucleobase is inserted into the target DNA by direct synthesis using modified phosphoramidites[4]. |
In vivo | 5-Aminouridine inhibits the incorporation of carbamoylaspartate into pyrimidines in living rat RNA and DNA, and the incorporation of [32P]phosphate into phospholipids and RNA nucleotides in rat liver slices and liver cancers [1]. |
Synonyms | 4-Chloro-2-isopropyl-5-methylphenol(chlorothymol) |
Molecular Weight | 259.22 |
Formula | C9H13N3O6 |
CAS No. | 2149-76-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (212.17 mM)
You can also refer to dose conversion for different animals. More
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5-Aminouridine 2149-76-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Antifungal Nucleoside Antimetabolite/Analog Influenza Virus 4-Chloro-2-isopropyl-5-methylphenol(chlorothymol) inhibitor inhibit