Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 3,770.00 | |
50 mg | 10-14 weeks | $ 4,980.00 | |
100 mg | 10-14 weeks | $ 7,000.00 |
Description | (RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid. |
In vitro | (RS)-AMPA activates glutamate/quisqualate receptors to induce depolarizing effects without influencing NMDA receptors. It enhances the discharge rate of spontaneously active neurons or triggers a brief burst of action potentials in inactive cells. The depolarization effect of (RS)-AMPA is dose-dependent but shows significant variability across different neurons. At concentrations of 10^-3 to 10^-4 M, (RS)-AMPA causes depolarizations in cultured rat spinal and brainstem neurons. Lower concentrations (10^-5 M) result in minimal depolarizations (3-7 mV), while higher concentrations (10^-4 M) generate larger depolarizations, varying from 4 to 33 mV [1]. |
Synonyms | (±)-AMPA |
Molecular Weight | 186.17 |
Formula | C7H10N2O4 |
CAS No. | 77521-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(RS)-AMPA 77521-29-0 Membrane transporter/Ion channel Neuroscience iGluR glutamate neurotransmitter kainic Ionotropic glutamate receptors NMDA Inhibitor CNS (RS) AMPA (±)-AMPA AMPA L-glutamic inhibit interneurones Depolarizations motoneurones (RS)AMPA inhibitor