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Cat No. | Product Name | Synonyms | Targets |
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T18984 | DNP-X, SE | 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester | Others |
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is an amine-reactive building block and can be recognized by anti-DNP antibodies. DNP-X, SE is also an excellent amine-reactive FRET quencher paired... | |||
T18983 | DNP-X acid | 6-((2,4-Dinitrophenyl)amino)hexanoic acid | Others |
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid) is an amine-reactive building block and can be recognized by anti-DNP antibodies. It is also an excellent amine-reactive FRET quencher paired with Trp or Tyr. | |||
TP1682L | Abz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base) | Others | |
Abz-FR-K(Dnp)-P-OH acetate is an excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1. | |||
T17841 | DNP-PEG6-Boc | DNP-PEG6-t-butyl ester | Others |
DNP-PEG6-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T15151 | DNP-PEG3-DNP | Others | |
DNP-PEG3-DNP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T36792 | DNP-INT | ||
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM). It inhibits electron flow from water to... | |||
T38378 | Dnp-PLAYWAR (trifluoroacetate salt) | ||
Dnp-PLAYWAR is a fluorogenic substrate for matrix metalloproteinase-8 (MMP-8) and MMP-26. The activity of MMP-8 and MMP-26 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis... | |||
T37024 | Mca-DEVDAPK(Dnp)-OH | ||
Mca-DEVDAPK(Dnp)-OH is a fluorescent substrate for caspase-3. | |||
T17839 | DNP-PEG4-DBCO | Others | |
DNP-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T36362 | Dnp-PLGMWSR (trifluoroacetate salt) | ||
Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. The activity of MMP-2 and MMP-9 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis t... | |||
T36363 | Dnp-RPLALWRS (trifluoroacetate salt) | ||
Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). The activity of MMP-7 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-t... | |||
T36361 | Dnp-PLALWAR (trifluoroacetate salt) | ||
Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8. The activity of MMP-1 and MMP-8 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis t... | |||
T40384 | Mca-Ala-Pro-Lys(Dnp)-OH | ||
Mca-Ala-Pro-Lys(Dnp)-OH, a specific quenched fluorogenic substrate for ACE2, enables the detection of ACE2 activity in various tissues including urinary, heart, and lung. | |||
T15153 | DNP-PEG4-alcohol | Others | |
DNP-PEG4-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ... | |||
T36360 | Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 | Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 | |
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be use... | |||
T15152 | DNP-PEG4-acid | Others | |
DNP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T15150 | DNP-PEG3-azide | Others | |
DNP-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T17837 | DNP-PEG12-acid | Others | |
DNP-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wi... | |||
T17840 | DNP-PEG6-acid | Others | |
DNP-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system wit... | |||
T15154 | DNP-PEG4-NHS ester | Others | |
DNP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T17838 | DNP-PEG12-NHS ester | Others | |
DNP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T15149 | DNP-NH-PEG4-C2-Boc | Others | |
DNP-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T15148 | DNP-NH-PEG2-C2-acid | Others | |
DNP-NH-PEG2-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
TP1634 | Bacterial Sortase Substrate III, Abz/DNP | ||
The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with it... | |||
TP1682 | Abz-FR-K(Dnp)-P-OH | ||
Excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1. | |||
TP1505 | MCA-SEVNLDAEFR-K(Dnp)-RR, amide | ||
MCA-SEVNLDAEFR-K(Dnp)-RR, amide is a FRET-based substrate. | |||
TP1322 | Bacterial Sortase Substrate III, Abz/DNP (TFA) | ||
Bacterial Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DN... | |||
T81720 | N,N'-Dinitrosopiperazine | 1,4-Dinitrosopiperazine,DNP | |
N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen targeting nasopharyngeal epithelium that promotes nasopharyngeal carcinoma (NPC) metastasis. It modulates various signaling pathways via protein pho... | |||
T81836 | Mca-SEVNLDAEFK(Dnp)-NH2 | ||
Mca-SEVNLDAEFK(Dnp)-NH2 is a fluorogenic substrate featuring a 7-methoxycoumarin moiety whose fluorescence is quenched by the adjacent 2,4-dinitrophenyl group through resonance energy transfer. This compound serves as a ... | |||
T31660 | Epsilon-Dinitrophenyllysine | Dinitrophenyl-lysine,Epsilon-dnp-lysine | |
epsilon-Dinitrophenyllysine is a bioactive chemical. | |||
T76269 | Dnp-PLGLWA-DArg-NH2 TFA | ||
Dnp-PLGLWA-DArg-NH2 TFA, a fluorogenic substrate specifically for MMP-1 and MMP-9, facilitates the quantification of MMP activity at an excitation wavelength of 280 nm and an emission wavelength of 360 nm [1] [2]. | |||
T76268 | Mca-VDQVDGW-Lys(Dnp)-NH2 | ||
Mca-VDQVDGW-Lys(Dnp)-NH2, a fluorogenic substrate specific to caspase-7, facilitates the quantification of caspase-7 activity. | |||
T83687 | Mca-RPPGFSAFK(Dnp)-OH TFA | (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(2,4-dinitrophenyl)-OH | |
Mca-RPPGFSAFK(Dnp)-OH, a fluorogenic substrate specifically designed for endothelin-converting enzyme-1 (ECE-1), enables the quantification of ECE-1 activity through its distinctive fluorescence signal. When ECE-1 cleave... | |||
T76090 | Mca-YVADAP-Lys(Dnp)-OH | ||
Mca-YVADAP-Lys(Dnp)-OH serves as a fluorogenic substrate specifically for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1]. | |||
T80048 | Mca-YVADAP-Lys(Dnp)-OH TFA | ||
Mca-YVADAP-Lys(Dnp)-OH TFA serves as a fluorogenic substrate specifically utilized for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1]. | |||
T78435 | Mca-(ala7,lys(dnp)9)-bradykinin | ||
Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,... | |||
T83686 | Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 acetate | ||
Mca-SEVNLDAEFR-K(Dnp)-RR-NH2 is a fluorogenic substrate designed for the quantification of β-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, ... | |||
T78430 | Bacterial Sortase Substrate III, Abz/DNP TFA | ||
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide used to monitor the activity of the Staphylococcus aureus transpeptidase sortase A (SrtA). This enzyme catalyzes the formation of... | |||
T83708 | Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA | Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 (Dpa = N-3-(2,4-dinitrophenyl)l-α,β-diaminopropionyl),FS-6 | |
Mca-KPLGL-Dap(Dnp)-AR-NH2 serves as a fluorogenic substrate specifically designed for matrix metalloproteinases (MMPs). This compound facilitates the quantification of MMP activity by releasing 7-methoxycoumarin-4-acetyl... | |||
T83719 | Mca-AVLQSGFR-K(Dnp)-K-NH2 TFA | ||
Mca-AVLQSGFR-K(Dnp)-K-NH2 serves as a fluorogenic substrate specifically designed for the main protease (Mpro) of the severe acute respiratory syndrome coronavirus (SARS-CoV), also referred to as 3C-like protease (3CLpro... | |||
T76190 | Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 | ||
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate employed for the quantification of matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26 activity. This compound facilitates the measurement of MMP-1, MMP-3, and... | |||
T78436 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | MMP | |
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1)... | |||
T78434 | Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA | ||
Mca-(endo-1α-Dap(Dnp))-TNF-α(-5 to +6) amide (human) TFA is a peptide that functions as a fluorescence resonance energy transfer (FRET)-based substrate, with its activity determined by the change in fluorescence intensit... | |||
T81838 | Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) | ||
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide utilized as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, wherein the cleavage-induced change in f... | |||
T83759 | MMP-3 Fluorogenic Substrate TFA | Mca-RPKPVE-Nval-WR-K(Dnp)-NH2,Matrix Metalloproteinase-3 Fluorogenic Substrate,Stromelysin-1 Fluorogenic Substrate | |
MMP-3 Fluorogenic Substrate, a compound designed for matrix metalloproteinase-3 (MMP-3) activity quantification, releases 7-methoxycoumarin-4-acetyl (Mca) upon MMP-3 cleavage. Mca's fluorescence, with excitation and emis... | |||
T37504 | Cathepsin D and E FRET Substrate | ||
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A. | |||
T7570 | RGD peptide (GRGDNP) | RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP | Apoptosis , Integrin |
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor. | |||
TP1311 | RGD peptide (GRGDNP) (TFA) (114681-65-1 free base) | RGD peptide (GRGDNP) (TFA) | |
RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. | |||
T36339 | Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp | ||
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair al... | |||
T36340 | Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) | ||
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fl... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3926 | Echinatin | Retrochalcone | Free radical scavengers |
Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv... | |||
TN2155 | Rhodiocyanoside A | Histamine Receptor | |
Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats. | |||
TN3914 | Echinatine | ATPase , IL Receptor , TNF | |
Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c... |