Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 168.00 | |
50 mg | In stock | $ 249.00 | |
100 mg | In stock | $ 369.00 | |
500 mg | In stock | $ 885.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 66.00 |
Description | Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. |
Source |
Synonyms | Retrochalcone |
Molecular Weight | 270.28 |
Formula | C16H14O4 |
CAS No. | 34221-41-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: Soluble
DMSO: 49 mg/mL(181.3 mM)
You can also refer to dose conversion for different animals. More
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Echinatin 34221-41-5 oxidation-reduction Free radical scavengers Retrochalcone inhibit Inhibitor inhibitor