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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16483 | PF-05105679 | TRP/TRPV Channel | |
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain. | |||
T9776 | TRPM4 inhibitor 8 | TRP/TRPV Channel | |
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion. | |||
T9335 | 1,1'-Methylenedi-2-naphthol | Squoxin | Others |
1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human). | |||
T3719 | Daminozide | Succinic Acid,DMASA,Aminozide | Histone Demethylase |
Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. | |||
T28020 | Mesendogen | TRP/TRPV Channel | |
Mesendogen is an inhibitor of TRPM6. Mesendogen alters magnesium homeostasis, promotes mesoderm and definitive endoderm differentiation. | |||
T62204 | NR2F6 modulator-1 | Others | |
NR2F6 modulator-1 is a potent modulator of nuclear receptor subfamily 2, group F, member 6 (NR2F6). NR2F6 modulator-1 can be used to study immune regulation and modulation of tumour stem cell activity. | |||
T10616 | BRM/BRG1 ATP Inhibitor-1 | Epigenetic Reader Domain | |
BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50... | |||
T16763 | RN-1747 | TRP/TRPV Channel | |
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV4 respectively). RN-1747 also antagonizes TRPM8 (IC50: 4 μM... | |||
T16745 | Rhosin hydrochloride | Apoptosis , Rho , Ras | |
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 o... | |||
T2024 | A-803467 | A 803467,A803467 | Sodium Channel |
A-803467 is a selective NaV1.8 channel blocker. | |||
TP2158 | TRV-120027 TFA | TRV-120027 TFA (1234510-46-3 free base) | RAAS , Arrestin |
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling. | |||
T23429 | KDM2/7-IN-1 | TC-E 5002 | Others |
Selective histone demethylase KDM2/7 subfamily inhibitor | |||
T68693 | AZ12099548 | ||
AZ12099548 is a transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist. | |||
T71359 | ArgTX-93 TFA | ||
ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs. | |||
T70716 | ArgTX-48 TFA | ||
ArgTX-48 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs. | |||
T63411 | CCG258747 | ||
CCG258747 is a novel, selective inhibitor of the GRK2 subfamily. | |||
T82579 | Dermaseptin-B9 | ||
Dermaseptin-B9, an antimicrobial peptide, has been isolated from the Phyllomedusinae subfamily of frogs [1]. | |||
T16746 | Rhosin | Rho | |
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. R... | |||
T37086 | PDDHV | ||
PDDHV is a resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1. It i... | |||
TP2287 | Rac GTPase fragment | Others | |
Rac GTPase fragment is a peptide with the sequence H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH, MW= 1019.15. Rac is a subfamily of the Rho family of GTPases, small signaling G proteins (more specifically a GTPase). |