ribonucleotide — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21195	AICAR monophosphate	Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide	Others
	AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.		Others
T9210	CD73-IN-4		CD73
	CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor		CD73
T14864	Caracemide	NSC-253272	Others , DNA/RNA Synthesis , Antibacterial
	Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.		Others , DNA/RNA Synthesis , Antibacterial
T0297	Clofarabine	Clofarex,Evoltra,Clolar	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
	Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T8855	Polydeoxyribonucleotide(Sodium salt)	Polydeoxyribonucleotide from salmon	Others
	Polydeoxyribonucleotide can improve secretion of various growth factors, promote collagen synthesis, and restore tensile strength of the Achilles tendon in a rat model with Achilles tendon injury.		Others
T0353	Osalmid	Oxaphenamide,4'-Hydroxysalicylanilide	HBV , DNA/RNA Synthesis
	Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).		HBV , DNA/RNA Synthesis
T31163	Cytidine 5'-diphosphate disodium	CDP sodium salt,Cytidine 5'-diphosphate disodium salt,Cytidine diphosphate sodium salt	Others
	Cytidine 5'-diphosphate disodium (CDP sodium salt) produces CTP to support DNA and RNA biosynthesis and ribonucleotide reductase to produce dCMP.		Others
T1982	3-AP	NSC663249,Triapine,PAN-811,OCX191	DNA/RNA Synthesis
	3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).		DNA/RNA Synthesis
T1705	5-Amino-3H-imidazole-4-Carboxamide	4-Amino-5-imidazolecarboxamide,AICA,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite
	5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparat...		Endogenous Metabolite
T5073	Inosine 5'-monophosphate disodium salt hydrate	Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,Disodium 5'-inosinate monohydrate	Others , Endogenous Metabolite
	Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.		Others , Endogenous Metabolite
T7525	Didox	NSC-324360	DNA/RNA Synthesis
	Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.		DNA/RNA Synthesis
T8800	NSAH	2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide	DNA/RNA Synthesis
	NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively...		DNA/RNA Synthesis
T4685	INOSINIC ACID	Inosine 5′-monophosphate,IMP,I-5'-P	Endogenous Metabolite
	Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the...		Endogenous Metabolite
T15826	Lometrexol	LY 264618,DDATHF	DHFR
	Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit ...		DHFR
T4809	Pyrimidine	Metadiazine	Others , Endogenous Metabolite
	Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...		Others , Endogenous Metabolite
T6501	Fludarabine Phosphate	NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T4826	L-Histidine monohydrochloride monohydrat		Others , Endogenous Metabolite
	Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ...		Others , Endogenous Metabolite
T29197	YZ51
	YZ51, a novel potent inhibitor of ribonucleotide reductase (RR), inhibits hepatitis B virus replication by targeting ribonucleotide reductase M2 protein.
T14147	Pelitrexol	AG 2037	DHFR
	Pelitrexol (AG 2037) is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor.		DHFR