Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 106.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 248.00 | |
50 mg | In stock | $ 368.00 | |
100 mg | In stock | $ 543.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 117.00 |
Description | Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies. |
In vitro | Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site[1]. |
In vivo | After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine[2]. |
Synonyms | NSC-253272 |
Molecular Weight | 189.17 |
Formula | C6H11N3O4 |
CAS No. | 81424-67-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (502.19 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Caracemide 81424-67-1 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Others DNA/RNA Synthesis Antibacterial hydroxamic Bacterial anticancer Escherichia reductase inhibit methylisocyanate toxicity NSC 253272 Inhibitor coli ribonucleotide NSC-253272 NSC253272 CNS MIC inhibitor