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Search Results for " p8 "

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Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP2389	Laminin B1 octapeptide P-8	Asp-pro-gln-tyr-ile-gln-ser-arg,Dpgyigsr
	Laminin B1 octapeptide P-8 is a synthetic laminin B1 chain octapeptide with laminin receptor binding ability.
T14987	CMP8		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, res...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T72784	OTUB1/USP8-IN-1		DUB
	OTUB1/USP8-IN-1 is a potent OTUB1/USP8 inhibitor with potential anticancer activity, with IC50 values of 0.17 and 0.28 nM for OTUB1 and USP8, respectively.OTUB1/USP8-IN-1 can be used in the study of non-small-cell lung c...		DUB
TP1893L1	[D-Trp8]-γ-MSH acetate(321351-81-9 free base)		Melanocortin Receptor
	[D-Trp8]-γ-MSH acetate(321351-81-9 free base) is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively) and displays anti-inflammatory ef...		Melanocortin Receptor
T67873	USP8-IN-3		DUB
	USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 μM and 6.01 μM, res...		DUB
T6990L	SNAP8 Acetate(868844-74-0,free base)		Others
	Diminishing the appearance of wrinkles.		Others
T60146	USP8-IN-1		DUB
	USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].		DUB
T2469	TP808	TP-808,TP 808	Others
	TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.		Others
T39615L	P8RI acetate		Integrin
	P8RI acetate is a biomimetic peptide of CD31 and an agonist of CDP8RI acetate shows an immunosuppressive effect through the restoration of the CD31 inhibitory pathway.		Integrin
T67876	USP8-IN-2		DUB
	USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.		DUB
T64001	MAP855
	MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutan...
T80135	Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11)
	Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11) is a somatostatin agonist utilized in cancer research [1].
T83546	(D-Trp8,D-Cys14)-Somatostatin-14
	(D-Trp8,D-Cys14)-Somatostatin-14, a synthetic analogue of somatostatin, is utilized in the study of metabolic-related diseases [1] [2].
T75854	[D-Trp8]-γ-MSH TFA
	[D-Trp8]-γ-MSH TFA is a potent, selective agonist for the melanocortin 3 (MC3) receptor, demonstrating IC50 values of 6.7 nM for hMC3, 600 nM for hMC4, and 340 nM for hMC5 in CHO cells, respectively. It shows potential i...
T124885	Antibiotic LL-P880y
	Antibiotic LL-P880y is a useful organic compound for research related to life sciences. The catalog number is T124885 and the CAS number is 41206-21-7.
T69769	BDP8900
	BDP8900 is a potent and selective MRCK inhibitor, reducing substrate phosphorylation. BDP8900 leads to morphological changes in cancer cells along with inhibition of their motility and invasive character.
T83493	[D-Trp8] Somatostatin-14
	[D-Trp8] Somatostatin-14 is a potent tetradecapeptide analog of native somatostatin, exhibiting increased efficacy [1].
T35137	WP814	WP 814,WP-814
	WP814 is a bioactive chemical.
T16878	SHP836		Others
	SHP836 is an inhibitor of SHP2 allosteric (IC50: 12 μM for the full-length SHP2).		Others
TP1893	[D-Trp8]-γ-MSH
	[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). [D-Trp8]-γ-MSH displays anti-inflammatory efficacy.
T39615	P8RI	D-P8RI
	P8RI (D-P8RI) is a CD31 biomimetic peptide and agonist that specifically targets the juxtamembrane amino acid sequence of the ectodomain of CD31. By restoring the CD31 inhibitory pathway, P8RI exhibits immunosuppressive ...
T73477	SHP844
	SHP844, a SHP2 inhibitor, exhibits an IC50 value of 18.9 µM. SHP2, a protein tyrosine phosphatase (PTP), plays a crucial role in modulating tyrosine phosphorylation levels, thereby influencing cell proliferation, differe...
T83494	[D-Trp8,Tyr11] Somatostatin
	[D-Trp8,Tyr11] Somatostatin, an analogue of the hormone somatostatin that modulates numerous bodily functions, is characterized by the substitution of DTrp8, which can enhance its stability [1].
T76612	(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide
	'(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analogue exhibiting varying affinity for somatostatin receptors, with dissociation constants (Kd) of 0.61 nM for SSTR5, 11.05 nM f...
T6990	SNAP8	Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2,SNAP 8,SNAP-8	Others
	SNAP8 (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-Nh2) is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation.		Others
T27851	LP8	LP 8,LP-8
	LP8 is a novel inhibitor of Trypanosoma cruzi CYP51.
T72784L	OTUB1/USP8-IN-1 HCl	OTUB1/USP8-IN-1 HCl（2858800-98-1 Free base）	DUB
	OTUB1/USP8-IN-1 HCL is a potent dual inhibitor of OTUB1 and USP8 with potential antitumour activity, inhibiting both OTUB1 and USP8. OTUB1/USP8-IN-1 may be used in the study of leukaemia.		DUB

Compounds

Laminin B1 octapeptide P-8

TP2389

Cat No.	Product Name	Synonyms	Targets
TN2376	Fructo-oligosaccharide DP8/GF7	Fructo-oligosaccharide DP8 / GF7	Others
	Fructo-oligosaccharide DP8/GF7 (Fructo-oligosaccharide DP8 / GF7) is a fructooligosaccharide (FOS) with a degree of polymerization (DP=8). It consists of seven fructose units connected by (2→1)-β-glycosidic bonds, featur...		Others
T32808	LL P880 beta	LL-P880 beta,LL-P880beta,LL-P880-beta,LLP880 beta
	LL P880 beta is a fungal metabolite.

Cat No.	Product Name	Species	Expression System
TMPY-01356	S100A8 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	S100A8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is P05109.
TMPY-03556	S100A8 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	S100A8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.3 kDa and the accession number is P27005.
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPY-06123	SARS-CoV-2 Nucleocapsid Protein (P80R, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (P80R, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P0DTC9.
TMPJ-01278	SENP8 Protein, Human, Recombinant (His)	Human	E. coli
	Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins ...
TMPY-05749	SARS-CoV-2 NSP8 Protein (Avi)	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPJ-01428	SARS-CoV-2 NSP8 Protein (His)	SARS-CoV-2	E. coli
	Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are...
TMPY-06416	SARS-CoV-2 NSP8 Protein	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPY-03623	NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxic...
TMPJ-00120	NKp80/KLRF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a ...
TMPK-00116	NKp80/KLRF1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate comp...