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Search Results for " p70-s6k "

Targets

12

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1746 LY-2584702 tosylate salt LY2584702 tosylate S6 Kinase
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.
T6159 LY-2584702 free base S6 Kinase , mTOR
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
T6303L CCT128930 hydrochloride CCT128930 hydrochloride(885499-61-6 Free base) Apoptosis , Akt , PKA , mTOR , Autophagy
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28...
T11928 M2698 MSC2363318A Akt , mTOR
M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity.
T2482 AT13148 ROCK , SGK , Akt , PKA , S6 Kinase
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
T6304 AT7867 Akt , PKA , S6 Kinase
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.
T1920 Capivasertib AZD5363 Akt , PKA , mTOR , Autophagy
Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.
T11900 LY-2584702 hydrochloride S6 Kinase
Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.
T39733 Hu7691 free base Akt
Hu7691 free base is an orally active, potent and selective Akt inhibitor with anti-proliferative and neurogenic effects on a variety of neuroblastoma cell lines.Hu7691 free base inhibits Akt1, Akt2, and Akt3 and induces ...
T10275 AKT-IN-3 Akt
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kin...
T10274 AKT-IN-2 Akt
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
T39899 Hu7691 Akt
Hu7691 is an orally active, selective and potent Akt inhibitor that inhibits Akt1, Akt2 and Akt3, inhibits proliferation of neuroblastoma cells and induces differentiation of neuroblastoma cells.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04540 S6K1/RPS6KB1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase...
TargetMol