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Search Results for " oligomer "

20

Compounds

Cat No. Product Name Synonyms Targets
T5447 Anle138b Beta Amyloid , Others
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease
T22012 7BIO FLT , DYRK , Aurora Kinase
7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.
T5650 2,2':5',2''-Terthiophene α-Terthienyl,Trithiophene Others , Antibacterial , Antibiotic
2,2':5',2''-Terthiophene (Trithiophene) (α-Terthiophene) is an oligomer of the heterocycle thiophene. α-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
T6909 NSC348884 Apoptosis , p53
NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.
T10789 Chitosan oligosaccharide COS AMPK
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. It has the ability to activate AMPK and simultaneously inhibit inflammatory signaling pathways, including NF-κB and MAPK.
T2S0633 Raspberry ketone Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone PPAR
1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can...
T12532 PQM130 Beta Amyloid
PQM130 is a neuroprotective compound ,and is a potential anti-AD drug.
T14199 ALZ-801 Valiltramiprosate Beta Amyloid
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m...
T38555 Chitotetraose tetrahydrochloride
Chitotetraose tetrahydrochloride is a short-chain chitin oligomer derived from arbuscular mycorrhizal (AM) fungi. This compound effectively activates the conserved symbiosis signaling pathway (CSSP) in actinorhizal plant...
T38981 D-Tetramannuronic acid
D-Tetramannuronic acid, an alginate oligomer, is derived from marine brown algae and certain Gram negative bacteria. It serves as a valuable compound for pain and vascular dementia research[4].
T40967 D-Octamannuronic acid
D-Octamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram-negative bacteria. It is research-oriented for the study of pain and vascular dementia [4].
T38860 Golodirsen Golodirsen,SRP-4053
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind and target exon 53 of dystrophin pre-mRNA, with applications in the investigation of Duchenne muscular dystrophy (DMD).
T35614 D-Trimannuronic acid
D-Trimannuronic acid is an alginate oligomer that originates from seaweed. It can induce TNF-α secretion by mouse macrophage cell lines, making it valuable in pain and vascular dementia research [1][2][3].
T34418 RS-0406 RS0406,Phenol
RS-0406 is a new type of β-flakes blocker, which can reverse amyloid β-induced cytotoxicity and long-term enhanced damage in vitro, and inhibit amyloid-oligomer-induced behavior deterioration in vivo.
T24779 SEN-1269
SEN-1269 is an amyloid-β (AB) aggregation inhibitor that acts by blocking Aβ(1-42) aggregation and protecting neuronal cell lines exposed to Aβ(1-42), reducing Aβ oligomer-induced LTP and memory deficits in vivo.
T21097 Decamethyltetrasiloxane Tetrasiloxane, decamethyl-,decamethyl-tetrasiloxan,D3780
Decamethyltetrasiloxane, a non-cyclic silicone oligomer, is used in the methylation of mercury(II) salts. It is transformed by a specific microflora. In the natural environment, it is degraded by mechanisms similar to ot...
T39277 D-Hexamannuronic acid
D-Hexamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram negative bacteria. This compound serves as a valuable tool for investigating pain and vascular dementia[4].
T39276 D-Pentamannuronic acid
D-Pentamannuronic acid is an alginate oligomer, synthesized by marine brown algae and a select group of Gram-negative bacteria. This chemical compound is valuable for research related to pain and vascular dementia[4].
T40966 D-Heptamannuronic acid
D-Heptamannuronic acid, an alginate oligomer, is derived from marine brown algae and a select group of Gram-negative bacteria. This compound serves as a valuable research tool in the study of pain and vascular dementia[4...
T81912 LSP-GR3 iGluR
LSP-GR3, a novel splice modulating oligomer (SMO) consisting of chemically-modified RNA oligonucleotides, potently and specifically directs the alternative splicing of GluR to promote GluR3-flip expression across the cen...
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