20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20533 | NNK | Nicotine-derived nitrosamine ketone | Lipoxygenase |
NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor. | |||
T68439 | Nicotine dicitrate | ||
Nicotine dicitrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also import... | |||
T23279 | RuBi-Nicotine | Others | |
Nicotinic receptor agonist | |||
TN4655 | Nicotine 1'-N-oxide | Others | |
Nicotine 1'-N-oxide is a natural product from tobacco smoke. | |||
T69439 | Nicotine tartrate | ||
Nicotine tartrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also importa... | |||
T70625 | Nicotine lactate | ||
Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical dru... | |||
T69804 | Nicotine monomethiodide | ||
Nicotine monomethiodide is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also i... | |||
T68289 | Nicotine hemicitrate | ||
Nicotine hemicitrate is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also impo... | |||
T10871 | CP-809101 hydrochloride | 5-HT Receptor | |
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors). | |||
T4246 | Varenicline dihydrochloride | AChR | |
Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist. | |||
T10432L | AZD-8529 mesylate | GluR | |
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 ... | |||
T20366 | Beta-Nicotyrine | Nicotyrine,alpha-Nicotyrine | Others |
beta-Nicotyrine is a tobacco alkaloids Metabolite in the liver. | |||
T69803 | Pelanserin Free Base | ||
Pelanserin Free Base is an antagonist of the 5-HT2 and α1-adrenergic receptors. | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T77676 | (Z)-Metanicotine 2HCl | (Z)-Metanicotine 2HCl(1129-68-6 Free base) | Others |
(Z)-Metanicotine 2HCl has analgesic activity and is used in the treatment of central system disorders. | |||
T69134 | Metanicotine | ||
Metanicotine is a selective nicotinic agonist with antinociceptive properties. | |||
T36709 | N’-Nitrosonornicotine | ||
N’-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. ... | |||
T13241 | UB 165 fumarate | UB-165 fumarate,UB165 fumarate | AChR |
UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain. | |||
T7671 | Myosmine | Others , AChR | |
Myosmine is a minor tobacco alkaloid that is structurally related to nicotine. | |||
T8044 | Ajmalicine | Lamuran,Delta-Yohimbine,Raubasine,Ajmalicin | Adrenergic Receptor |
Ajmalicine (Raubasine) (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, IC50 = 72.3 μM. Ajmalicine a... |