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UB 165 fumarate

Catalog No. T13241 CAS 2454492-43-2

Synonyms: UB-165 fumarate, UB165 fumarate

UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain.

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UB 165 fumarate, CAS 2454492-43-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 350.00
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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Purity: 98.91%

ee: 100%

Biological Description

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Description	UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain.
Targets&IC50	Nicotine (rat brain):ki:0.27 nM , Nicotine (rat brain):0.27 nM(ki)
In vitro	UB-165 fumarate exhibits an EC50 value of 88 nM for stimulating [3H]-dopamine release from striatal synaptosomes.[1]

Synonyms	UB-165 fumarate, UB165 fumarate
Molecular Weight	350.8
Formula	C17H19ClN2O4
CAS No.	2454492-43-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91.

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Keywords

UB 165 fumarate 2454492-43-2 Neuroscience AChR UB165 Fumarate UB-165 fumarate UB165 fumarate UB-165 Fumarate UB 165 Fumarate inhibitor inhibit

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