malarial — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6512	Tectol		Transferase , Parasite
	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...		Transferase , Parasite
T4333	Quinine dihydrochloride	Quinine bimuriate	Others
	Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).		Others
T20712	Conessine	Conessinum,Wrightine,Roquessine,Neriine,Konessin	Histamine Receptor
	Conessine (Conessinum), a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.		Histamine Receptor
T6631	Quinine hydrochloride dihydrate	Quinine HCl Dihydrate	Potassium Channel , Parasite
	Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.		Potassium Channel , Parasite
T2481	Ascomycin	FK520,Immunomycin,FR-900520	Phosphatase , Others , Antibiotic , Parasite , Antifungal
	Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.		Phosphatase , Others , Antibiotic , Parasite , Antifungal
T2895	Lupeol	Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis , Androgen Receptor , Akt
	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.		Apoptosis , Androgen Receptor , Akt
T79535	Antimalarial agent 30		Parasite
	Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.		Parasite
T22381	Antimalarial agent 14	4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone	Others
	Antimalarial agent 14 (NSC-102533) is a bioactive chemical.		Others
T10336	Antimalarial agent 1		Parasite
	Antimalarial agent 1 is an effective antimalarial agent.		Parasite
T9984	Antimalarial agent 13	N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine	Parasite
	Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.		Parasite
T63655	Antimalarial agent 9
	Antimalarial agent 9 is an effective antimalarial agent, a quinoline-imidazole derivative compound. antimalarial agent 9 showed significant in vitro antimalarial effects against CQ-susceptible strains (IC50-0.14 μM) and ...
T63595	Antimalarial agent 16
	Antimalarial agent 16 is a parasite inhibitor that exhibits antimalarial effects and inhibits the growth of Plasmodium falciparum with an IC50 value of 2.0 nM.
T62537	Antimalarial agent 7
	Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.
T62300	Antimalarial agent 11
	Antimalarial agent 11 (compound 1) is a potent antimalarial agent, a spirocyclic chromane. Antimalarial agent 11 is able to act on D6 (EC50: 1.48 μM) and ARC08-022 (EC50: 1.81 μM).
T75067	Antimalarial agent 19		Parasite
	Antimalarial agent 19 (compound 6e) exhibits antimalarial activity against the blood stages of P. falciparum K1 and P. berghei, with EC50 values of 0.3 µM and 15.3 µM, respectively. It demonstrates good aqueous solubilit...		Parasite
T79534	Antimalarial agent 29		Parasite
	Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P. berghei liver stage parasite load, exhibiting an effective concentration (EC50) of 5.2 μM [1].		Parasite
T78951	Antimalarial agent 24		Parasite
	Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM and exhibits a cytotoxicity threshold (CC50) exceeding 200 μM...		Parasite
T74845	Antimalarial agent 23
	Antimalarial agent 23, a benzimidazole-based compound, exhibits potent antimalarial activity, demonstrated by its low IC50 values of 0.08 μM for PfNF54 and 0.10 μM for PfK1, respectively. This compound effectively inhibi...
T79335	Antimalarial agent 31		Parasite
	Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].		Parasite
T61200	Antimalarial agent 3
	Antimalarial agent 3, an antimalarial agent, exhibits potent activity against Plasmodium with an IC50 of 0.035 μM. Furthermore, it demonstrates an exceptionally high selectivity index in relation to mammalian cells.