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Ascomycin

Catalog No. T2481   CAS 104987-12-4
Synonyms: FK520, Immunomycin, FR-900520

Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.

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Ascomycin Chemical Structure
Ascomycin, CAS 104987-12-4
Pack Size Availability Price/USD Quantity
5 mg In stock $ 36.00
10 mg In stock $ 52.00
50 mg In stock $ 63.00
100 mg In stock $ 81.00
500 mg In stock $ 192.00
1 mL * 10 mM (in DMSO) In stock $ 54.00
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Purity: 99.94%
Purity: 99.64%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
Targets&IC50 Calcineurin phosphatase:49 nM
Synonyms FK520, Immunomycin, FR-900520
Molecular Weight 792.01
Formula C43H69NO12
CAS No. 104987-12-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 39.6 mg/mL (50 mM)

Ethanol: 39.6 mg/mL (50 mM)

TargetMolReferences and Literature

1. Hatanaka H, et al. J Antibiot (Tokyo). 1988, 41(11), 1592-1601. 2. Revill WP, et al. J Pharmacol Exp Ther. 2002, 302(3), 1278-1285. 3. Monaghan P, et al. J Infect Dis. 2005, 191(8), 1342-1349. 4. Vázquez-López A, et al. Pharmacol Biochem Behav. 2006 Jul;84(3):511-6.

Related compound libraries

This product is contained In the following compound libraries:
Antiparasitic Natural Product Library Anti-Parasitic Compound Library Microbial Natural Product Library Covalent Natural Product Library Antibiotics Library Bioactive Compound Library Metabolism Compound Library Lipid Metabolism Compound Library Natural Product Library for HTS Apoptosis Compound Library

Related Products

Related compounds with same targets
Chloroquine phosphate SDZ285428 Chloroquine Piperonyl butoxide AP-C5 Metronidazole Cowaxanthone B Nitromide

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Keywords

Ascomycin 104987-12-4 Metabolism Microbiology/Virology Others Phosphatase Antibiotic Antifungal Parasite anti-fungal FR 900520 FK520 FKBP macrolide Fungal Inhibitor FK-520 inhibit Immunomycin FR900520 FK506-binding protein immunosuppressant FR-900520 FK 520 anti-spasmodic FKBP12 anti-malarial inhibitor

 

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