mtor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36316	mTOR inhibitor-8	mTOR-IN-8	mTOR , Autophagy
	mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activity. mTOR inhibitor-8 inhibits the growth of A549 cells, which can be used to study non-small cell lung cancer.		mTOR , Autophagy
T63399L	mTOR/HDAC-IN-1 HCl	mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)	HDAC , mTOR
	mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.		HDAC , mTOR
T12123	mTOR inhibitor-3		mTOR
	mTOR inhibitor-3 is a selective mTOR inhibitor (Ki= 1.5 nM). mTOR inhibitor-3 inhibits mTORC1 and mTORC2 in cellular and in vivo experiments.		mTOR
T5338	mTOR inhibitor-1		mTOR , Autophagy
	C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.		mTOR , Autophagy
T12589	PI3Kα/mTOR-IN-1		PI3K , mTOR
	PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR. PI3Kα/mTOR-IN-1 shows an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 12.5 nM and 10.6 nM for mTOR and PI3Kα in a cell free assay , respectively.		PI3K , mTOR
T12459	PI3K/mTOR Inhibitor-2		PI3K , mTOR
	PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16,1 and 4.7 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. PI3K/mTOR Inhibitor-2 has antitumor activity.		PI3K , mTOR
T67703	mTOR inhibitor 9b		mTOR
	mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA with IC50s of 0.76 nm and 1.262 µM, respectively.mTOR inhibitor 9b possesses anticancer activity and can be used to ...		mTOR
T67705	mTOR inhibitor 9a
	mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.
T67702	mTOR inhibitor 9d		PI3K , mTOR
	mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer.		PI3K , mTOR
T67704	mTOR inhibitor 9e		PI3K , mTOR
	mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for mTOR and PI3Kα, respectively.		PI3K , mTOR
T67701	mTOR inhibitor 9f		PI3K , mTOR
	mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.		PI3K , mTOR
T67706	mTOR inhibitor 9c		PI3K , mTOR
	mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for mTOR and PI3Kα, respectively.		PI3K , mTOR
T9310	mTOR inhibitor 13		PI3K , mTOR
	mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.		PI3K , mTOR
T60564	PI3K/Akt/mTOR-IN-2		Apoptosis , Akt , PI3K , mTOR
	PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MDA-MB-231 cells with an IC50 of 2.29 μM.PI3K/Akt/mTOR-IN-2 exhibits anticancer activity and induces c...		Apoptosis , Akt , PI3K , mTOR
T12124	mTOR inhibitor-2		mTOR
	mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).		mTOR
T12460	PI3K/mTOR Inhibitor-1		PI3K
	PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual inhibitor of PI3K/mTOR (PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ/mTOR with IC50s of 20/376/204/46/186 nM)		PI3K
T11544	HDACs/mTOR Inhibitor 1		HDAC
	HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα).		HDAC
T9309	mTOR inhibitor 11
	mTOR inhibitor 11 is a useful organic compound for research related to life sciences. The catalog number is T9309 and the CAS number is 1195785-35-3.
T79211	mTOR inhibitor-11		mTOR
	mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 of 21 nM for pS6. It also exhibits inhibitory activity against pCHK1 and PDE4D with IC50 values of 17.2 μM and 17.0 μM,...		mTOR
T81744	mTOR inhibitor-14		mTOR
	mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1].		mTOR