Powder: -20°C for 3 years
In solvent: -80°C for 2 years
<a href="/target/HDAC" style="display: inline; color: #c13a36">HDAC</a>s/<a href="/target/mTOR" style="display: inline; color: #c13a36">mTOR</a> Inhibitor 1 is a dual <a href="/target/HDAC" style="display: inline; color: #c13a36">HDAC</a>s and mammalian target of Rapamycin (<a href="/target/mTOR" style="display: inline; color: #c13a36">mTOR</a>) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for <a href="/target/HDAC" style="display: inline; color: #c13a36">HDAC</a>1, <a href="/target/HDAC" style="display: inline; color: #c13a36">HDAC</a>6, <a href="/target/mTOR" style="display: inline; color: #c13a36">mTOR</a> and <a href="/target/PI3K" style="display: inline; color: #c13a36">PI3K</a>α).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 8-10 weeks | $ 970.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα). |
Targets&IC50 | mTOR:1.2 nM, HDAC6:1.8 nM, HDAC1:0.19 nM |
In vitro | HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo. |
Molecular Weight | 566.65 |
Formula | C28H38N8O5 |
CAS No. | 2271413-06-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 32.5 mg/mL (57.35 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HDACs/mTOR Inhibitor 1 2271413-06-8 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC Inhibitor inhibitor inhibit