Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 93.00 | |
25 mg | In stock | $ 189.00 | |
50 mg | In stock | $ 297.00 | |
100 mg | In stock | $ 493.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation. |
In vitro | The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and dose314 dependent. The IC50 of C-4 at 24 h is calculated as 3.176 μM. |
Molecular Weight | 363.21 |
Formula | C16H15BrN2O3 |
CAS No. | 468747-17-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 70 mg/mL (192.72 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
mTOR inhibitor-1 468747-17-3 Autophagy PI3K/Akt/mTOR signaling mTOR mTOR inhibitor1 Mammalian target of Rapamycin inhibit mTOR inhibitor 1 Inhibitor inhibitor