Powder: -20°C for 3 years | In solvent: -80°C for 1 year
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 828.00 | |
10 mg | In stock | $ 1,130.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,900.00 |
Description | mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer. |
Targets&IC50 | Phosphatidylinositol 3-kinase PIK3CA:324 nM, mTOR:0.31 nM, LNCaP cells:180 nM |
In vitro | mTOR inhibitor 9d (compound 9d) inhibitory concentration against the proliferation of human prostate cancer LNCaP cell line by cellular proliferation assay with IC50 is 180 nM.[2] |
Molecular Weight | 425.5 |
Formula | C21H23N5O3S |
CAS No. | 1144075-38-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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mTOR inhibitor 9d 1144075-38-6 PI3K/Akt/mTOR signaling PI3K mTOR 1(2hydroxyethyl)3{4[4(8oxa3azabicyclo[3.2.1]oct3yl)thieno[3,2d]pyrimidin2yl]phenyl}urea inhibitor inhibit