lines — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6512	Tectol		Transferase , Parasite
	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...		Transferase , Parasite
T22336	Galloflavin		Dehydrogenase
	Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.		Dehydrogenase
T7200	TAK-960		PLK
	TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.		PLK
T38562	AKN-028		FLT
	AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.		FLT
T12477	Uzansertib phosphate	INCB053914 phosphate	Pim
	Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).		Pim
T19514	Phosphatidylcholines,soya	Soybean phosphatidylcholine	Others
	Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes.		Others
T36013	Lysophosphatidylcholines	Lyso-Lecithins (egg)	Apoptosis
	Lysophosphatidylcholines (Lyso-Lecithins (egg)) are orally active lipids that induce cell damage and apoptosis, and induce demyelination. Lysophosphatidylcholines play a role in mediating inflammation, fibrosis, and canc...		Apoptosis
T76130	Acetylcholinesterase
	Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes th...
T124793	Cholinesulfuric acid.
	Cholinesulfuric acid. is a useful organic compound for research related to life sciences. The catalog number is T124793 and the CAS number is 4858-96-2.
T65419	8-Quinolinesulfonic Acid
	8-Quinolinesulfonic Acid is a useful organic compound for research related to life sciences. The catalog number is T65419 and the CAS number is 85-48-3.
T82148	Hydrogenated soya phosphatidylcholines
	Hydrogenated soya phosphatidylcholines, a natural compound, enhances the controlled release of water-soluble drugs in oral drug delivery systems by improving drug loading and solubility [1].
T10395L	ATM-3507		Others
	ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.		Others
T15578	Indotecan	NSC-724998,LMP-400	Topoisomerase
	Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).		Topoisomerase
T31821	Fluorizoline
	Fluorizoline is an inducer of p53 independent apoptosis in a variety of tumor cell lines.
TN3049	4-Methoxycinnamyl alcohol		Others
	4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox...		Others
T2090	Lexibulin	CYT-997	Apoptosis , Reactive Oxygen Species , Microtubule Associated
	Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this...
T21804	GW 610		Others
	GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0....		Others
T19712	Levoglucosenone		Others
	Levoglucosenone has cytotoxic. It against human hepatocarcinoma cell lines.		Others
T73494	TNG908
	TNG908, a MTAP-cooperative PRMT5 inhibitor capable of penetrating the blood-brain barrier, demonstrates 15-fold greater selectivity for MTAP cell lines over MTAP WT (wild type) cell lines. Its application is primarily in...
T11337	Fumarate hydratase-IN-1		Others
	Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor.		Others