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Search Results for " indolinone "

5

Compounds

Cat No. Product Name Synonyms Targets
T22432 SU5208 3-[(Thien-2-yl)methylene]-2-indolinone VEGFR
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).
T8496 MAZ51 Apoptosis , VEGFR
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Fr16741 Oxindole Indolin-2-one Others , HIV Protease
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ...
T0374 Sunitinib Malate Sutent,SU 11248 (Malate),SU 11248,Sunitinib Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit.
T28874 SU11652 SU-11652,SU 11652
SU11652 is a potent cell-permeable pyrrole-indolinone compound. SU11652 acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor with greater selectivity for PDGFR-β (PDGFRβ, IC50 = 3 nM), Flk-1 (VEGF...
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