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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22432 | SU5208 | 3-[(Thien-2-yl)methylene]-2-indolinone | VEGFR |
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2). | |||
T8496 | MAZ51 | Apoptosis , VEGFR | |
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. | |||
Fr16741 | Oxindole | Indolin-2-one | Others , HIV Protease |
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ... | |||
T0374 | Sunitinib Malate | Sutent,SU 11248 (Malate),SU 11248,Sunitinib | Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy |
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit. | |||
T28874 | SU11652 | SU-11652,SU 11652 | |
SU11652 is a potent cell-permeable pyrrole-indolinone compound. SU11652 acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor with greater selectivity for PDGFR-β (PDGFRβ, IC50 = 3 nM), Flk-1 (VEGF... |