good — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40130	Nur77 modulator 1	Nur77 modulator 1	Others
	Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell ...		Others
T20573	Carbetamide	Legurame,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B	Others
	Carbetamide (Caswell No. 159B) is a herbicide with a good reproduction of mobility in the soil.		Others
T3920	Pseudoginsenoside F11	Ginsenoside A1	Others , Endogenous Metabolite
	Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m...		Others , Endogenous Metabolite
T13506	3β-Ursodeoxycholic acid	Isoursodeoxycholic acid
	3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid (administered orally has shown good tolerability and good intestinal absorption. 3β-Ursodeoxycholic acid can undergo enzymatic iso...
T11103	DS18561882		Others
	DS18561882 also inhibited MTHFD1 (IC50=0.57).DS18561882 had good oral drug kinetics.DS18561882 is a potent isozyme-selective methylene tetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with IC50 value of 0.0063.		Others
T19858	Brodimoprim		DHFR , Antibacterial
	Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR). Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic profile.		DHFR , Antibacterial
T1834	CX-6258	CX 6258	Pim
	CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.		Pim
T8343	8-Hydroxy-2'-deoxyguanosine	8-OHdG,8-Hydroxydeoxyguanosine,8-Hydroxy-2-Deoxyguanosine,2'-Deoxy-8-oxoguanosine,8 OHdG,8-Oxo-dG,8 Oxo dG,8-Oxo-2'-deoxyguanosine	Endogenous Metabolite
	8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases.		Endogenous Metabolite
T28829	Soquinolol	Soquinolol mucate	Adrenergic Receptor
	Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a long duration of action.		Adrenergic Receptor
T2S1434	Bergaptol	5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-Hydroxypsoralen	P450
	1. Bergaptol (4-Hydroxybergapten) shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.		P450
T14313	Apricitabine	AVX754,SPD754	HIV Protease , DNA/RNA Synthesis
	Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a...		HIV Protease , DNA/RNA Synthesis
T27748L	KRP-199 sodium	KRP-199 sodium(221164-28-9 Free base)	GluR
	KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.		GluR
T2249	XEN445	XEN 445,XEN-445	Lipase
	XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.		Lipase
TN7237	5,7-dimethoxy-2-benzofuran-1(3H)-one	5,7-dimethoxyphthalide
	5,7-dimethoxy-2-benzofuran-1(3H)-one (5,7-dimethoxyphthalide) is a phthalide isolated from Italian waxflower with good anti-inflammatory activity.
T12649	Ibafloxacine	S25930,Ibafloxacin,R835	Antifungal
	Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against Bartonella.		Antifungal
T6S1918	Schisantherin B	Gomisin-B,Wuweizi ester-B,Schizantherin-B	Beta Amyloid , Others
	1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Beta Amyloid , Others
T26969	CCT365623	CCT-365623,CCT 365623	Monoamine Oxidase
	CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy.		Monoamine Oxidase
T4S1820	Parishin	Parishin A	Others
	Parishin (Parishin A) A is isolated from the rhizomes of Gastrodia elata. It has good neuroprotective effects against brain disorders.		Others
T6S0107	Peimine	Wanpeinine A,Dihydroisoimperialine,Verticine	Others
	1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.		Others
TN1137	Isobutylshikonin		Others
	Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·.		Others