ganglion — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2026	CYM5442		S1P Receptor , LPL Receptor
	CYM5442 is an S1P agonist, targeting to Sphingosine.		S1P Receptor , LPL Receptor
T7748	Dermorphin TFA		Others , Opioid Receptor
	Dermorphin TFA is a new class of opioids-like peptides		Others , Opioid Receptor
T22733	DL-AP5		NMDAR
	DL-AP5 is a NMDA antagonist.		NMDAR
T7404	Dermorphin		Opioid Receptor
	Dermorphin is agonist of μ-opioid receptor (MOR) agonist.		Opioid Receptor
T5913	Sulbutiamine	Bisibuthiamine	Antioxidant
	Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.		Antioxidant
TP1283L	VIP(6-28)(human, rat, porcine, bovine) acetate		Others
	VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG).		Others
T72662	NMDAR/TRPM4-IN-2		ERK , TRP/TRPV Channel , NMDAR , iGluR
	NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot...		ERK , TRP/TRPV Channel , NMDAR , iGluR
T28431	PNU109291	PNU-109291,PNU 109291
	PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.
T3289L	Amifostine Hydrate
	Amifostine Hydrate is a radiation protective agent that induces splenic vasodilation and blocks autonomic ganglion.
TP2393	Neurotensin-related hexapeptide	Lant-6
	Neurotensin-related hexapeptide exists in retinal ganglion cells and in their central projections in pigeons and may be utilized as a neuroactive substance by the central terminals of numerous retinal ganglion cells in b...
TP1934	L-R4W2
	Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.
T28987	TN-871 HCl	TN-871 dihydrochloride,TN871,TN 871,TN-871
	TN-871 is a potassium and calcium channel antagonist. TN-871 modulates transmitter release from preganglionic nerve terminals without changing the postsynaptic sensitivity of the ganglion cells to ACh.
T25110	AS1069562	AS-1069562,AS 1069562
	AS1069562 is an inhibitor of serotonin (5-HT) and norepinephrine (NE) reuptake which acts by notably restoring reduced insulin-like growth factor 1 and fibroblast growth factor 2 mRNA levels in dorsal root ganglion and s...
T80443	ω-Conotoxin MVIID	SNX-238	Calcium Channel
	ω-Conotoxin MVIID (SNX-238) is a peptide from the Conus genus that inhibits the ω-Conotoxin-GVIA-sensitive, high-threshold calcium (Ca 2+) current in fish retinal ganglion cells [1].		Calcium Channel
T68811	Trimetaphan camsilate
	Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathe...
T16135	MRS 1523		Others
	MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 recept...		Others
T35889	PB2
	PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficac...
T62265	(+)-Sparteine sulfate pentahydrate
	(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.
TP2070	BDS I
	Potent and reversible Kv3.4 potassium channel blocker (IC50 = 47 nM); also attenuates inactivation of sodium currents by acting on Nav1.7 and Nav1.3 channels. Enhances TTX-sensitive sodium currents in rat small dorsal ro...
T37296	GI-530159
	TREK1 and TREK2 channel activator (EC50 = 0.76 μM in Rb efflux assay in TREK1-expressing CHO cells). Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane pot...