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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23550 | YM-750 | YM 750 | Acyltransferase |
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest... | |||
T3244 | 2-Deoxy-2-sulfoamino-D-glucose sodium | N-Sulfo-D-glucosamine sodium salt,N-Sulfo-glucosamine sodium salt,GlcN-2S,2-Deoxy-2-sulfamino-D-glucopyranose | Others , Endogenous Metabolite |
2-Deoxy-2-sulfoamino-D-glucose sodium (GlcN-2S) is possible to effect reaction at arthritis. | |||
T13171 | TMN355 | Others | |
TMN355 is a potent chemical inhibitor of cyclophilin A and reduces foam cell formation and cytokine secretion,and is used for atherosclerosis. | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
T27977 | Manzamine A | Keramamine A | |
Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram nega... | |||
TN4600 | Myrianthic acid | PAFR , AChR | |
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-density lipoproteins at a 50 uM concentration. Myrianthic a... | |||
T73906 | Myristoyl glutamic acid sodium | ||
Myristoyl glutamic acid sodium, a surfactant linked to (amino acid), is frequently utilized in cosmetics/creams. This compound exhibits mild cleansing effects, generates foam, and possesses somewhat bacteriostatic proper... | |||
T70356 | F-1394 | ||
F-1394 is an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. F-1394 both prevents the formation of atherosclerosis and accelerates its regression without affecting the serum TC level, indicating that F-1394 acts ... | |||
TN5097 | Tanshindiol C | LDL , Histone Methyltransferase | |
Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique... | |||
T35985 | CAY10487 | ||
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in hig... |