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Search Results for " fear "

13

Compounds

Cat No. Product Name Synonyms Targets
T8458 CNQX disodium iGluR
CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
T8511 TM38837 Cannabinoid Receptor
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
T2710 TCS 1102 OX Receptor
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
T7178 CNQX FG9065 GluR , iGluR
CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
T5828 MS21570 GPR
MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.
T16378 Ogerin Others , 5-HT Receptor , Adenosine Receptor
Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak an...
TP2026 GRP (porcine)
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA re...
T39120 Fluoroethylnormemantine
Fluoroethylnormemantine, a derivative of Memantine, acts as an N-methyl-D-aspartate (NMDA) receptor antagonist. It can function as a positron emission tomography (PET) tracer, known as [18F]-fluoroethylnormemantine. This...
T39119 Fluoroethylnormemantine hydrochloride
Fluoroethylnormemantine hydrochloride, a Memantine derivative, functions as an antagonist for the N-methyl-D-aspartate (NMDA) receptor. It can also serve as a positron emission tomography (PET) tracer, specifically as [1...
T60964 Tasipimidine sulfate
Tasipimidine sulfate can be used for the research of situational anxiety and fear. Tasipimidine sulfate is a selective and orally active agonist of α2A-adrenoceptor with a pEC50 of 7.57 for human α2A-adrenoceptor [1].
TP2091 Antisauvagine-30
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAM...
T83825 Trofinetide acetate NNZ-2566
Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig...
T37370 Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red an...
TargetMol