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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82424 | Experimental allergic encephalitogenic peptide (human) | ||
Experimental allergic encephalitogenic peptide (human), an EAE peptide, induces encephalomyelitis in guinea pigs [1]. | |||
T8543 | KN-92 hydrochloride | CaMK | |
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM. | |||
T12079 | ML604440 | Proteasome | |
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor. | |||
T24984 | 5J-4 | Calcium Channel | |
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. | |||
T4530 | KN-92 phosphate | KN92-H3PO4 | CaMK |
KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). | |||
T25829 | Mopidamol | RA233,RA 233,RA-233,Rapenton,OLX 102 | PDE |
Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes. | |||
T1017 | Fluorothyl | Fluoroethyl,Flurothyl,Bis(2,2,2-trifluoroethyl) ether | Others |
Fluorothyl (Bis(2,2,2-trifluoroethyl) ether) is a convulsant used in experimental animals. | |||
T5517 | (R)-Carisbamate | Others | |
(R)-Carisbamate is the R-isomer of Carisbamate . Carisbamate is an experimental anticonvulsant drug. | |||
TN1026 | Vomicine | Others | |
Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals. | |||
T2394 | Pixantrone dimaleate | BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate | Topoisomerase |
Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug. | |||
T7629 | Olesoxime | NSC 21311,TRO 19622 | Mitochondrial Metabolism |
Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug. | |||
T7298 | FT011 | Others | |
FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy. | |||
T22963 | McN-A 343 | AChR | |
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ... | |||
T71691 | Pumafentrine | BY 343 | PDE |
Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice. | |||
T28722 | SCH 57790 | SCH57790,SCH-57790 | AChR |
SCH 57790 is a novel and selective muscarinic M(2) receptor antagonist that releases acetylcholine and enhances cognition in experimental animals for the treatment of Alzheimer's disease. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
T35367 | Thioacetamide | TAA | Others |
Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats. | |||
T68100 | Mifentidine | DA 4577 | Histamine Receptor |
Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers. | |||
T9106 | E1231 | Sirtuin | |
E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression. | |||
T0804 | Pilocarpine Hydrochloride | NSC 5746 HCl,Pilocarpine HCl,(+)-Pilocarpine hydrochloride | AChR |
Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy. |