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Search Results for " dioxygenase "

20

Compounds

Cat No. Product Name Synonyms Targets
T4S0051 Coptisine sulfate Indoleamine 2,3-Dioxygenase (IDO)
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
T11615 IDO-IN-12 IDO , Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).
T5S0053 Coptisine Coptisin Indoleamine 2,3-Dioxygenase (IDO)
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...
T3S1967 (S)-Indoximod N-ME-Tryptophan,Abrine,L-Abrine Others , Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...
T39598 4-Chlorocatechol Others
4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2].
T11901 IDO1-IN-5 IDO , Indoleamine 2,3-Dioxygenase (IDO)
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
T11616 IDO-IN-13 GS-4361 IDO , Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).
T9164 BMS-986242 BMS986242 IDO , Indoleamine 2,3-Dioxygenase (IDO)
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
T10199 GNF-PF-3777 8-Nitrotryptanthrin IDO , Indoleamine 2,3-Dioxygenase (IDO)
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).
T2647 IDO5L INCB024360 analogue,INCB14943 IDO , Indoleamine 2,3-Dioxygenase (IDO)
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).
T4532 Linrodostat BMS-986205 IDO , Indoleamine 2,3-Dioxygenase (IDO)
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
TQ0071 Navoximod GDC-0919,NLG-​919 Indoleamine 2,3-Dioxygenase (IDO)
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).
T4307 PF-06840003 EOS200271,PF 06840003 IDO , Indoleamine 2,3-Dioxygenase (IDO)
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.
T7181 IDO-IN-1 Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)
T3548 Epacadostat INCB 024360,IDO Inhibitor 1 IDO , Indoleamine 2,3-Dioxygenase (IDO)
Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells.
T1847 Necrostatin-1 Nec-1,Necrostatin 1 Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T4142 PCC0208009 IDO inhibitor 1,DO-IN-2,IDO-IN-2 Indoleamine 2,3-Dioxygenase (IDO)
PCC0208009 (IDO-IN-2) is an IDO inhibitor.
T1806 IDO-IN-7 NLG919,Navoximod,NLG-919 analogue,GDC-0919 Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
T5S0056 Coptisine chloride Q-100696,NSC-119754 Indoleamine 2,3-Dioxygenase (IDO) , Influenza Virus , Antibacterial
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds.

Compounds

Coptisine sulfate
T4S0051
Synonym:
Target: Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-12
T11615
Synonym:
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
Coptisine
T5S0053
Synonym: Coptisin
Target: Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod
T3S1967
Synonym: N-ME-Tryptophan,Abrine,L-Abrine
Target: Others, Indoleamine 2,3-Dioxygenase (IDO)
4-Chlorocatechol
T39598
Synonym:
Target: Others
IDO1-IN-5
T11901
Synonym:
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-13
T11616
Synonym: GS-4361
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
BMS-986242
T9164
Synonym: BMS986242
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
GNF-PF-3777
T10199
Synonym: 8-Nitrotryptanthrin
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
IDO5L
T2647
Synonym: INCB024360 analogue,INCB14943
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
Linrodostat
T4532
Synonym: BMS-986205
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
Navoximod
TQ0071
Synonym: GDC-0919,NLG-​919
Target: Indoleamine 2,3-Dioxygenase (IDO)
PF-06840003
T4307
Synonym: EOS200271,PF 06840003
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-1
T7181
Synonym:
Target: Indoleamine 2,3-Dioxygenase (IDO)
Epacadostat
T3548
Synonym: INCB 024360,IDO Inhibitor 1
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
Necrostatin-1
T1847
Synonym: Nec-1,Necrostatin 1
Target: Indoleamine 2,3-Dioxygenase (IDO), Ferroptosis, Autophagy, RIP kinase
Palmatine chloride
T2718
Synonym:
Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase
PCC0208009
T4142
Synonym: IDO inhibitor 1,DO-IN-2,IDO-IN-2
Target: Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-7
T1806
Synonym: NLG919,Navoximod,NLG-919 analogue,GDC-0919
Target: Indoleamine 2,3-Dioxygenase (IDO)
Coptisine chloride
T5S0056
Synonym: Q-100696,NSC-119754
Target: Indoleamine 2,3-Dioxygenase (IDO), Influenza Virus, Antibacterial
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TargetMol