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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4S0051 | Coptisine sulfate | Indoleamine 2,3-Dioxygenase (IDO) | |
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. | |||
T11615 | IDO-IN-12 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO). | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T3S1967 | (S)-Indoximod | N-ME-Tryptophan,Abrine,L-Abrine | Others , Indoleamine 2,3-Dioxygenase (IDO) |
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L... | |||
T39598 | 4-Chlorocatechol | Others | |
4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2]. | |||
T11901 | IDO1-IN-5 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | |||
T11616 | IDO-IN-13 | GS-4361 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM). | |||
T9164 | BMS-986242 | BMS986242 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer. | |||
T10199 | GNF-PF-3777 | 8-Nitrotryptanthrin | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM). | |||
T2647 | IDO5L | INCB024360 analogue,INCB14943 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). | |||
T4532 | Linrodostat | BMS-986205 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor. | |||
TQ0071 | Navoximod | GDC-0919,NLG-919 | Indoleamine 2,3-Dioxygenase (IDO) |
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). | |||
T4307 | PF-06840003 | EOS200271,PF 06840003 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor. | |||
T7181 | IDO-IN-1 | Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.) | |||
T3548 | Epacadostat | INCB 024360,IDO Inhibitor 1 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells. | |||
T1847 | Necrostatin-1 | Nec-1,Necrostatin 1 | Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase |
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO. | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T4142 | PCC0208009 | IDO inhibitor 1,DO-IN-2,IDO-IN-2 | Indoleamine 2,3-Dioxygenase (IDO) |
PCC0208009 (IDO-IN-2) is an IDO inhibitor. | |||
T1806 | IDO-IN-7 | NLG919,Navoximod,NLG-919 analogue,GDC-0919 | Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor. | |||
T5S0056 | Coptisine chloride | Q-100696,NSC-119754 | Indoleamine 2,3-Dioxygenase (IDO) , Influenza Virus , Antibacterial |
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds. |