crosslinking — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7545	6-Aminonicotinamide		Others
	6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.		Others
T2210	Genipin	(+)-Genipin	Others , Autophagy
	Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.		Others , Autophagy
T35648	4-Thiouridine		Others
	4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...		Others
T19958	2-Iminothiolane HCl	2-Iminothiolane,Traut's reagent,Trauts reagent,2-IT	Others
	2-Iminothiolane HCl (Trauts reagent) is a useful RNA-protein crosslinking reagent and an effective thiolation reagent for the introduction of sulphydryl groups into oligosaccharides.		Others
T1616	Cefotiam hydrochloride	Pansporin,SCE-963 hydrochloride,Pansporine,Cefotiam dihydrochloride,Halospor	Antibacterial , Antibiotic
	Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicilli...		Antibacterial , Antibiotic
T14061	EMCS	6-Maleimidohexanoic acid N-hydroxysuccinimide ester	Others
	EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective ...		Others
T4047	Bisantrene	CL216942	Topoisomerase
	Bisantrene (CL216942) is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and ...		Topoisomerase
T4704	L-Anserine nitrate	L-Anserine nitrate salt	Others , Endogenous Metabolite
	L-Anserine nitrate (L-Anserine nitrate salt) is a dipeptide found in most animal tissues. In model systems it is a potent Antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymatic protein glycatio...		Others , Endogenous Metabolite
T4657	WHI-P97		JAK
	WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane ...		JAK
T5024	Cefotiam Hexetil Hydrochloride		Antibacterial , Antibiotic
	Cefotiam Hexetil Hydrochloride is a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.		Antibacterial , Antibiotic
T38951	Isatuximab	SAR-650984,hu38SB19,Isatuximab-irfc	Apoptosis , CD38
	Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ...		Apoptosis , CD38
T38294	4-Deoxypyridoxine hydrochloride		S1P Receptor
	4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib...		S1P Receptor
T39757	EC2629	EC2629
	EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent.
T29964	Ametantrone Acetate	CI-881
	Ametantrone Acetate is a topoisomerase II inhibitor of anthrapyrazole family, which can lead to DNA covalent crosslinking.
T19193	Amotosalen hydrochloride	S-59	Others
	Amotosalen hydrochloride (S-59) is a light-activated, RNA-, DNA-crosslinking psoralen compound and is used to neutralize pathogens.		Others
T19942	SBA Crosslinker	SBA Cross-linker,SBA Cross linker
	SBA crosslinker is a sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents k...
T19560	SGD-1882	PBD dimer	Others
	SGD-1882 is a agent of cytotoxic, DNA minor-groove crosslinking pyrrolobenzodiazepine (PBD) dimer, and acting as the payload for ADCs.		Others
T30598	BS2G-d4 Deuterated Crosslinker	D4-BS2G,BS2G-d4
	BS2G-d4 or Bis(Sulfosuccinimidyl) 2,2,4,4-glutarate-d4, is a water-soluble and membrane impermeable protein crosslinking agent.
T24453	Metamelfalan	NSC-67781,Metamelfalanum,NSC67781,NSC 67781,m-L-Sarcolysin
	Metamelfalan is an alkylating nitrogen mustard with potential antineoplastic activity. It causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.
T19941	MBS Crosslinker	MBS protein crosslinker
	MBS crosslinker is a non-cleavable, water-insoluble, heterobifunctional protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog is SMPB crosslinker SATA Protein Modifier can be used to add su...